B7Z1T4 (B7Z1T4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cytohesin-1 Ensembl ENSP00000465940 Ensembl ENSP00000466512

Submitted name:
cDNA FLJ54415, highly similar to Cytohesin-1 EMBL BAH11620.1
Submitted name:
cDNA, FLJ79176, highly similar to Cytohesin-1 EMBL BAH14648.1

Gene names

Name:

CYTH1 Ensembl ENSP00000465940 Ensembl ENSP00000466512

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAH11620.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. RuleBase RU003350 Contains 1 SEC7 domain. SAAS SAAS023394

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	establishment of epithelial cell polarity Inferred from electronic annotation. Source: Compara regulation of ARF protein signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	tight junction Inferred from electronic annotation. Source: Compara
Molecular_function	ARF guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: InterPro phospholipid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z1T4 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: C08318AD7469BD02	FASTA	339	39,470
	10 20 30 40 50 60 MQRNKQVAMG RKKFNMDPKK GIQFLIENDL LKNTCEDIAQ FLYKGEGLNK TAIGDYLGER 70 80 90 100 110 120 DEFNIQVLHA FVELHEFTDL NLVQALRQFL WSFRLPGEAQ KIDRMMEAFA QRYCQCNNGV 130 140 150 160 170 180 FQSTDTCYVL SFAIIMLNTS LHNPNVKDKP TVERFIAMNR GINDGGDLPE ELLRNLYESI 190 200 210 220 230 240 KNEPFKIPED DGNDLTHTFF NPDREGWLLK LGGGRVKTWK RRWFILTDNC LYYFEYTTDK 250 260 270 280 290 300 EPRGIIPLEN LSIREVEDSK KPNCFELYIP DNKDQVIKAC KTEADGRVVE GNHTVYRISA 310 320 330 PTPEEKEEWI KCIKAAISRD PFYEMLAARK KKVSSTKRH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L. , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C. Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAH11620.1.
[3]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL BAH14648.1.
[4]	Ensembl Submitted (NOV-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC022966 Genomic DNA. No translation available. AC099804 Genomic DNA. No translation available. AK293894 mRNA. Translation: BAH11620.1. AK316277 mRNA. Translation: BAH14648.1.
IPI	IPI01015548.
UniGene	Hs.191215.
3D structure databases
SMR	B7Z1T4. Positions 1-332.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000585509; ENSP00000465940; ENSG00000108669. ENST00000589297; ENSP00000466512; ENSG00000108669.
Organism-specific databases
HGNC	HGNC:9501. CYTH1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG002647.
Gene expression databases
ArrayExpress	B7Z1T4.
Family and domain databases
Gene3D	1.10.1000.11. 1 hit. 2.30.29.30. 1 hit.
InterPro	IPR011993. PH_like_dom. IPR001849. Pleckstrin_homology. IPR000904. Sec7. IPR023394. SEC7_alpha_orthog. [Graphical view]
Pfam	PF00169. PH. 1 hit. PF01369. Sec7. 1 hit. [Graphical view]
SMART	SM00233. PH. 1 hit. SM00222. Sec7. 1 hit. [Graphical view]
SUPFAM	SSF48425. Sec7. 1 hit.
PROSITE	PS50003. PH_DOMAIN. 1 hit. PS50190. SEC7. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35478815.

Entry information

Entry name

B7Z1T4_HUMAN

Accession

Primary (citable) accession number: B7Z1T4

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.