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Protein

Non-specific serine/threonine protein kinase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiB7Z1G6.

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiB7Z1G6.
PRIDEiB7Z1G6.

Structurei

3D structure databases

ProteinModelPortaliB7Z1G6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 183Protein kinaseInterPro annotationAdd BLAST183
Domaini522 – 571KA1 (kinase-associated)InterPro annotationAdd BLAST50

Phylogenomic databases

HOVERGENiHBG106273.

Family and domain databases

Gene3Di3.30.310.80. 1 hit.
InterProiIPR028375. KA1/Ssp2_C.
IPR001772. KA1_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF02149. KA1. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF103243. SSF103243. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50032. KA1. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z1G6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNFSNIMNY MKLLGQSDLP RIKTEIEALK NLRHQHICQL YHVLETANKI
60 70 80 90 100
FMVLEENLLF DEYHKLKLID FGLCAKPKGN KDYHLQTCCG SLAYAAPELI
110 120 130 140 150
QGKSYLGSEA DVWSMGILLY VLMCGFLPFD DDNVMALYKK IMRGKYDVPK
160 170 180 190 200
WLSPSSILLL QQMLQVDPKK RISMKNLLNH PWIMQDYNYP VEWQSKNPFI
210 220 230 240 250
HLDDDCVTEL SVHHRNNRQT MEDLISLWQY DHLTATYLLL LAKKARGKPV
260 270 280 290 300
RLRLSSFSCG QASATPFTDI KSNNWSLEDV TASDKNYVAG LIDYDWCEDD
310 320 330 340 350
LSTGAATPRT SQFTKYWTES NGVESKSLTP ALCRTPANKL KNKENVYTPK
360 370 380 390 400
SAVKNEEYFM FPEPKTPVNK NQHKREILTT PNRYTTPSKA RNQCLKETPI
410 420 430 440 450
KIPVNSTGTD KLMTGVISPE RRCRSVELDL NQAHMEETPK RKGAKVFGSL
460 470 480 490 500
ERGLDKVITV LTRSKRKGSA RDGPRRLKLH YNVTTTRLVN PDQLLNEIMS
510 520 530 540 550
ILPKKHVDFV QKGYTLKCQT QSDFGKVTMQ FELEVCQLQK PDVVGIRRQR
560 570
LKGDAWVYKR LVEDILSSCK V
Length:571
Mass (Da):65,648
Last modified:March 3, 2009 - v1
Checksum:iA8C887E4D8DA07A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293423 mRNA. Translation: BAH11502.1.
RefSeqiNP_001243620.1. NM_001256691.1.
UniGeneiHs.184339.

Genome annotation databases

GeneIDi9833.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293423 mRNA. Translation: BAH11502.1.
RefSeqiNP_001243620.1. NM_001256691.1.
UniGeneiHs.184339.

3D structure databases

ProteinModelPortaliB7Z1G6.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiB7Z1G6.
PRIDEiB7Z1G6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9833.

Organism-specific databases

CTDi9833.

Phylogenomic databases

HOVERGENiHBG106273.

Enzyme and pathway databases

SignaLinkiB7Z1G6.

Miscellaneous databases

GenomeRNAii9833.

Family and domain databases

Gene3Di3.30.310.80. 1 hit.
InterProiIPR028375. KA1/Ssp2_C.
IPR001772. KA1_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamiPF02149. KA1. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF103243. SSF103243. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50032. KA1. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z1G6_HUMAN
AccessioniPrimary (citable) accession number: B7Z1G6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 30, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.