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Protein
Submitted name:

cDNA FLJ59467, highly similar to Cytochrome P450 2C8 (EC 1.14.14.1)

Gene

CYP2C8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ59467, highly similar to Cytochrome P450 2C8 (EC 1.14.14.1)Imported
Gene namesi
Name:CYP2C8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000138115.13
HGNCiHGNC:2622 CYP2C8

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138115

Expressioni

Gene expression databases

BgeeiENSG00000138115

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00880000137861
HOVERGENiHBG015789

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z1F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIVVFHGY EAVKEALIDN GEEFSGRGNS PISQRITKGL GIISSNGKRW
60 70 80 90 100
KEIRRFSLTT LRNFGMGKRS IEDRVQEEAH CLVEELRKTK ASPCDPTFIL
110 120 130 140 150
GCAPCNVICS VVFQKRFDYK DQNFLTLMKR FNENFRILNS PWIQVCNNFP
160 170 180 190 200
LLIDCFPGTH NKVLKNVALT RSYIREKVKE HQASLDVNNP RDFIDCFLIK
210 220 230 240 250
MEQEKDNQKS EFNIENLVGT VADLFVAGTE TTSTTLRYGL LLLLKHPEVT
260 270 280 290 300
AKVQEEIDHV IGRHRSPCMQ DRSHMPYTDA VVHEIQRYSD LVPTGVPHAV
310 320 330 340 350
TTDTKFRNYL IPKGTTIMAL LTSVLHDDKE FPNPNIFDPG HFLDKNGNFK
360 370 380 390 400
KSDYFMPFSA GKRICAGEGL ARMELFLFLT TILQNFNLKS VDDLKNLNTT
410 420
AVTKGIVSLP PSYQICFIPV
Length:420
Mass (Da):47,786
Last modified:March 3, 2009 - v1
Checksum:iE74FEC3C5A3453AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359672 Genomic DNA No translation available.
AK293327 mRNA Translation: BAH11491.1
RefSeqiNP_001185782.1, NM_001198853.1
NP_001185783.1, NM_001198854.1
NP_001185784.1, NM_001198855.1
UniGeneiHs.709188

Genome annotation databases

EnsembliENST00000539050; ENSP00000442343; ENSG00000138115
ENST00000623108; ENSP00000485110; ENSG00000138115
GeneIDi1558
UCSCiuc010qoa.2 human

Similar proteinsi

Entry informationi

Entry nameiB7Z1F5_HUMAN
AccessioniPrimary (citable) accession number: B7Z1F5
Secondary accession number(s): F5H7Q9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 20, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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