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Protein
Submitted name:

Cytochrome P450 2C8

Gene

CYP2C8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 2C8Imported
Submitted name:
cDNA FLJ59467, highly similar to Cytochrome P450 2C8 (EC 1.14.14.1)Imported
Gene namesi
Name:CYP2C8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000138115.13.
HGNCiHGNC:2622. CYP2C8.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000138115.

Expressioni

Gene expression databases

BgeeiENSG00000138115.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
GeneTreeiENSGT00880000137861.
HOVERGENiHBG015789.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z1F5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIVVFHGY EAVKEALIDN GEEFSGRGNS PISQRITKGL GIISSNGKRW
60 70 80 90 100
KEIRRFSLTT LRNFGMGKRS IEDRVQEEAH CLVEELRKTK ASPCDPTFIL
110 120 130 140 150
GCAPCNVICS VVFQKRFDYK DQNFLTLMKR FNENFRILNS PWIQVCNNFP
160 170 180 190 200
LLIDCFPGTH NKVLKNVALT RSYIREKVKE HQASLDVNNP RDFIDCFLIK
210 220 230 240 250
MEQEKDNQKS EFNIENLVGT VADLFVAGTE TTSTTLRYGL LLLLKHPEVT
260 270 280 290 300
AKVQEEIDHV IGRHRSPCMQ DRSHMPYTDA VVHEIQRYSD LVPTGVPHAV
310 320 330 340 350
TTDTKFRNYL IPKGTTIMAL LTSVLHDDKE FPNPNIFDPG HFLDKNGNFK
360 370 380 390 400
KSDYFMPFSA GKRICAGEGL ARMELFLFLT TILQNFNLKS VDDLKNLNTT
410 420
AVTKGIVSLP PSYQICFIPV
Length:420
Mass (Da):47,786
Last modified:March 3, 2009 - v1
Checksum:iE74FEC3C5A3453AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359672 Genomic DNA. No translation available.
AK293327 mRNA. Translation: BAH11491.1.
RefSeqiNP_001185782.1. NM_001198853.1.
NP_001185783.1. NM_001198854.1.
NP_001185784.1. NM_001198855.1.
UniGeneiHs.709188.

Genome annotation databases

EnsembliENST00000539050; ENSP00000442343; ENSG00000138115.
ENST00000623108; ENSP00000485110; ENSG00000138115.
GeneIDi1558.
UCSCiuc010qoa.2. human.

Similar proteinsi

Entry informationi

Entry nameiB7Z1F5_HUMAN
AccessioniPrimary (citable) accession number: B7Z1F5
Secondary accession number(s): F5H7Q9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 27, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported