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B7WPN2

- B7WPN2_HUMAN

UniProt

B7WPN2 - B7WPN2_HUMAN

Protein
Submitted name:

Cytosolic phospholipase A2 epsilon

Gene

PLA2G4E

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. phospholipase A2 activity Source: Ensembl

    GO - Biological processi

    1. phospholipid catabolic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cytosolic phospholipase A2 epsilonImported
    Gene namesi
    Name:PLA2G4EImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:24791. PLA2G4E.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiB7WPN2.

    Expressioni

    Gene expression databases

    ArrayExpressiB7WPN2.
    BgeeiB7WPN2.

    Structurei

    3D structure databases

    ProteinModelPortaliB7WPN2.
    SMRiB7WPN2. Positions 59-150, 317-861.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 C2 domain.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000231788.
    HOVERGENiHBG080412.
    KOiK16342.
    OMAiYPKYFQP.
    OrthoDBiEOG7Z0JVQ.
    PhylomeDBiB7WPN2.
    TreeFamiTF325228.

    Family and domain databases

    Gene3Di2.60.40.150. 1 hit.
    InterProiIPR016035. Acyl_Trfase/lysoPLipase.
    IPR000008. C2_dom.
    IPR002642. LysoPLipase_cat_dom.
    [Graphical view]
    PfamiPF00168. C2. 1 hit.
    PF01735. PLA2_B. 1 hit.
    [Graphical view]
    SMARTiSM00239. C2. 1 hit.
    SM00022. PLAc. 1 hit.
    [Graphical view]
    SUPFAMiSSF49562. SSF49562. 1 hit.
    SSF52151. SSF52151. 1 hit.
    PROSITEiPS50004. C2. 1 hit.
    PS51210. PLA2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7WPN2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLQASEGCP GLGTNVFVPQ SPQTDEEGSR SGRSFSEFED TQDLDTPGLP    50
    PFCPMAPWGS EEGLSPCHLL TVRVIRMKNV RQADMLSQTD CFVSLWLPTA 100
    SQKKLRTRTI SNCPNPEWNE SFNFQIQSRV KNVLELSVCD EDTVTPDDHL 150
    LTVLYDLTKL CFRKKTHVKF PLNPQGMEEL EVEFLLEESP SPPETLVTNG 200
    VLVSRQVSCL EVHAQSRRRR KREKMKDLLV MVNESFENTQ RVRPCLEPCC 250
    PTSACFQTAA CFHYPKYFQS QVHVEVPKSH WSCGLCCRSR KKGPISQPLD 300
    CLSDGQVMTL PVGESYELHM KSTPCPETLD VRLGFSLCPA ELEFLQKRKV 350
    VVAKALKQVL QLEEDLQEDE VPLIAIMATG GGTRSMTSMY GHLLGLQKLN 400
    LLDCASYITG LSGATWTMAT LYRDPDWSSK NLEPAIFEAR RHVVKDKLPS 450
    LFPDQLRKFQ EELRQRSQEG YRVTFTDFWG LLIETCLGDE RNECKLSDQR 500
    AALSCGQNPL PIYLTINVKD DVSNQDFREW FEFSPYEVGL QKYGAFIPSE 550
    LFGSEFFMGR LVKRIPESRI CYMLGLWSSI FSLNLLDAWN LSHTSEEFFH 600
    RWTREKVQDI EDEPILPEIP KCDANILETT VVIPGSWLSN SFREILTHRS 650
    FVSEFHNFLS GLQLHTNYLQ NGQFSRWKDT VLDGFPNQLT ESANHLCLLD 700
    TAFFVNSSYP PLLRPERKAD LIIHLNYCAG SQTKPLKQTC EYCTVQNIPF 750
    PKYELPDENE NLKECYLMEN PQEPDAPIVT FFPLINDTFR KYKAPGVERS 800
    PEELEQGQVD IYGPKTPYAT KELTYTEATF DKLVKLSEYN ILNNKDTLLQ 850
    ALRLAVEKKK RLKGQCPS 868
    Length:868
    Mass (Da):99,190
    Last modified:February 10, 2009 - v1
    Checksum:iF9A6F33880A5409F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC039056 Genomic DNA. No translation available.
    RefSeqiNP_001193599.1. NM_001206670.1.
    UniGeneiHs.668060.

    Genome annotation databases

    EnsembliENST00000399518; ENSP00000382434; ENSG00000188089.
    GeneIDi123745.
    KEGGihsa:123745.
    UCSCiuc021sjp.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC039056 Genomic DNA. No translation available.
    RefSeqi NP_001193599.1. NM_001206670.1.
    UniGenei Hs.668060.

    3D structure databases

    ProteinModelPortali B7WPN2.
    SMRi B7WPN2. Positions 59-150, 317-861.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi B7WPN2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000399518 ; ENSP00000382434 ; ENSG00000188089 .
    GeneIDi 123745.
    KEGGi hsa:123745.
    UCSCi uc021sjp.1. human.

    Organism-specific databases

    CTDi 123745.
    HGNCi HGNC:24791. PLA2G4E.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000231788.
    HOVERGENi HBG080412.
    KOi K16342.
    OMAi YPKYFQP.
    OrthoDBi EOG7Z0JVQ.
    PhylomeDBi B7WPN2.
    TreeFami TF325228.

    Miscellaneous databases

    GenomeRNAii 123745.
    NextBioi 81141.

    Gene expression databases

    ArrayExpressi B7WPN2.
    Bgeei B7WPN2.

    Family and domain databases

    Gene3Di 2.60.40.150. 1 hit.
    InterProi IPR016035. Acyl_Trfase/lysoPLipase.
    IPR000008. C2_dom.
    IPR002642. LysoPLipase_cat_dom.
    [Graphical view ]
    Pfami PF00168. C2. 1 hit.
    PF01735. PLA2_B. 1 hit.
    [Graphical view ]
    SMARTi SM00239. C2. 1 hit.
    SM00022. PLAc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49562. SSF49562. 1 hit.
    SSF52151. SSF52151. 1 hit.
    PROSITEi PS50004. C2. 1 hit.
    PS51210. PLA2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
      Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
      , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
      Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB7WPN2_HUMAN
    AccessioniPrimary (citable) accession number: B7WPN2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 10, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3