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B7WPN2

- B7WPN2_HUMAN

UniProt

B7WPN2 - B7WPN2_HUMAN

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Protein
Submitted name:

Cytosolic phospholipase A2 epsilon

Gene
PLA2G4E
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. phospholipase A2 activity Source: Ensembl

GO - Biological processi

  1. phospholipid catabolic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cytosolic phospholipase A2 epsilonImported
Gene namesi
Name:PLA2G4EImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:24791. PLA2G4E.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB7WPN2.

Expressioni

Gene expression databases

ArrayExpressiB7WPN2.
BgeeiB7WPN2.

Structurei

3D structure databases

ProteinModelPortaliB7WPN2.
SMRiB7WPN2. Positions 59-150, 317-861.

Family & Domainsi

Sequence similaritiesi

Contains 1 C2 domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231788.
HOVERGENiHBG080412.
KOiK16342.
OMAiYPKYFQP.
OrthoDBiEOG7Z0JVQ.
PhylomeDBiB7WPN2.
TreeFamiTF325228.

Family and domain databases

Gene3Di2.60.40.150. 1 hit.
InterProiIPR016035. Acyl_Trfase/lysoPLipase.
IPR000008. C2_dom.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamiPF00168. C2. 1 hit.
PF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTiSM00239. C2. 1 hit.
SM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMiSSF49562. SSF49562. 1 hit.
SSF52151. SSF52151. 1 hit.
PROSITEiPS50004. C2. 1 hit.
PS51210. PLA2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7WPN2-1 [UniParc]FASTAAdd to Basket

« Hide

MSLQASEGCP GLGTNVFVPQ SPQTDEEGSR SGRSFSEFED TQDLDTPGLP    50
PFCPMAPWGS EEGLSPCHLL TVRVIRMKNV RQADMLSQTD CFVSLWLPTA 100
SQKKLRTRTI SNCPNPEWNE SFNFQIQSRV KNVLELSVCD EDTVTPDDHL 150
LTVLYDLTKL CFRKKTHVKF PLNPQGMEEL EVEFLLEESP SPPETLVTNG 200
VLVSRQVSCL EVHAQSRRRR KREKMKDLLV MVNESFENTQ RVRPCLEPCC 250
PTSACFQTAA CFHYPKYFQS QVHVEVPKSH WSCGLCCRSR KKGPISQPLD 300
CLSDGQVMTL PVGESYELHM KSTPCPETLD VRLGFSLCPA ELEFLQKRKV 350
VVAKALKQVL QLEEDLQEDE VPLIAIMATG GGTRSMTSMY GHLLGLQKLN 400
LLDCASYITG LSGATWTMAT LYRDPDWSSK NLEPAIFEAR RHVVKDKLPS 450
LFPDQLRKFQ EELRQRSQEG YRVTFTDFWG LLIETCLGDE RNECKLSDQR 500
AALSCGQNPL PIYLTINVKD DVSNQDFREW FEFSPYEVGL QKYGAFIPSE 550
LFGSEFFMGR LVKRIPESRI CYMLGLWSSI FSLNLLDAWN LSHTSEEFFH 600
RWTREKVQDI EDEPILPEIP KCDANILETT VVIPGSWLSN SFREILTHRS 650
FVSEFHNFLS GLQLHTNYLQ NGQFSRWKDT VLDGFPNQLT ESANHLCLLD 700
TAFFVNSSYP PLLRPERKAD LIIHLNYCAG SQTKPLKQTC EYCTVQNIPF 750
PKYELPDENE NLKECYLMEN PQEPDAPIVT FFPLINDTFR KYKAPGVERS 800
PEELEQGQVD IYGPKTPYAT KELTYTEATF DKLVKLSEYN ILNNKDTLLQ 850
ALRLAVEKKK RLKGQCPS 868
Length:868
Mass (Da):99,190
Last modified:February 10, 2009 - v1
Checksum:iF9A6F33880A5409F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC039056 Genomic DNA. No translation available.
RefSeqiNP_001193599.1. NM_001206670.1.
UniGeneiHs.668060.

Genome annotation databases

EnsembliENST00000399518; ENSP00000382434; ENSG00000188089.
GeneIDi123745.
KEGGihsa:123745.
UCSCiuc021sjp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC039056 Genomic DNA. No translation available.
RefSeqi NP_001193599.1. NM_001206670.1.
UniGenei Hs.668060.

3D structure databases

ProteinModelPortali B7WPN2.
SMRi B7WPN2. Positions 59-150, 317-861.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B7WPN2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000399518 ; ENSP00000382434 ; ENSG00000188089 .
GeneIDi 123745.
KEGGi hsa:123745.
UCSCi uc021sjp.1. human.

Organism-specific databases

CTDi 123745.
HGNCi HGNC:24791. PLA2G4E.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000231788.
HOVERGENi HBG080412.
KOi K16342.
OMAi YPKYFQP.
OrthoDBi EOG7Z0JVQ.
PhylomeDBi B7WPN2.
TreeFami TF325228.

Miscellaneous databases

GenomeRNAii 123745.
NextBioi 81141.

Gene expression databases

ArrayExpressi B7WPN2.
Bgeei B7WPN2.

Family and domain databases

Gene3Di 2.60.40.150. 1 hit.
InterProi IPR016035. Acyl_Trfase/lysoPLipase.
IPR000008. C2_dom.
IPR002642. LysoPLipase_cat_dom.
[Graphical view ]
Pfami PF00168. C2. 1 hit.
PF01735. PLA2_B. 1 hit.
[Graphical view ]
SMARTi SM00239. C2. 1 hit.
SM00022. PLAc. 1 hit.
[Graphical view ]
SUPFAMi SSF49562. SSF49562. 1 hit.
SSF52151. SSF52151. 1 hit.
PROSITEi PS50004. C2. 1 hit.
PS51210. PLA2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the DNA sequence and duplication history of human chromosome 15."
    Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A.
    , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
    Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB7WPN2_HUMAN
AccessioniPrimary (citable) accession number: B7WPN2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: July 9, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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