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B7WPH3

- B7WPH3_HUMAN

UniProt

B7WPH3 - B7WPH3_HUMAN

Protein
Submitted name:

Cat eye syndrome critical region protein 2

Gene

CECR2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 2 (03 Nov 2009)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cat eye syndrome critical region protein 2Imported
    Gene namesi
    Name:CECR2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 22

    Organism-specific databases

    HGNCiHGNC:1840. CECR2.

    Expressioni

    Gene expression databases

    ArrayExpressiB7WPH3.
    BgeeiB7WPH3.

    Structurei

    3D structure databases

    ProteinModelPortaliB7WPH3.
    SMRiB7WPH3. Positions 229-354.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    BromodomainSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000081808.
    HOVERGENiHBG081078.
    OrthoDBiEOG7ZGX27.

    Family and domain databases

    Gene3Di1.20.920.10. 1 hit.
    InterProiIPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR029614. CECR2.
    [Graphical view]
    PANTHERiPTHR22880:SF123. PTHR22880:SF123. 1 hit.
    PfamiPF00439. Bromodomain. 1 hit.
    [Graphical view]
    PRINTSiPR00503. BROMODOMAIN.
    SMARTiSM00297. BROMO. 1 hit.
    [Graphical view]
    SUPFAMiSSF47370. SSF47370. 1 hit.
    PROSITEiPS00633. BROMODOMAIN_1. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7WPH3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYKEDPVQGK SNGELSLSRE SEGQKNVSSI PGKTGKRRGR PPKRKKLQEE     50
    ILLSEKQEEN SLASEPQTRH GSQGPGQGTW WLLCQTEEEW RQVTESFRER 100
    TSLRERQLYK LLSEDFLPEI CNMIAQKGKR PQRTKAELHP RWMSDHLSIK 150
    PVKQEETPVL TRIEKQKRKE EEEERQILLA VQKKEQEQML KEERKRELEE 200
    KVKAVEDRAK RRKLREERAW LLAQGKELPP ELSHLDPNSP MREEKKTKDL 250
    FELDDDFTAM YKVLDVVKAH KDSWPFLEPV DESYAPNYYQ IIKAPMDISS 300
    MEKKLNGGLY CTKEEFVNDM KTMFRNCRKY NGESSEYTKM SDNLERCFHR 350
    AMMKHFPGED GDTDEEFWIR EDEKREKRRS RAGRSGGSHV WTRSRDPEGS 400
    SRKQQPMENG GKSLPPTRRA PSSGDDQSSS STQPPREVGT SNGRGFSHPL 450
    HCGGTPSQAP FLNQMRPAVP GTFGPLRGSD PATLYGSSGV PEPHPGEPVQ 500
    QRQPFTMQPP VGINSLRGPR LGTPEEKQMC GGLTHLSNMG PHPGSLQLGQ 550
    ISGPSQDGSM YAPAQFQPGF IPPRHGGAPA RPPDFPESSE IPPSHMYRSY 600
    KYLNRVHSAV WNGNHGATNQ GPLGPDEKPH LGPGPSHQPR TLGHVMDSRV 650
    MRPPVPPNQW TEQSGFLPHG VPSSGYMRPP CKSAGHRLQP PPVPAPSSLF 700
    GAPAQALRGV QGGDSMMDSP EMIAMQQLSS RVCPPGVPYH PHQPAHPRLP 750
    GPFPQVAHPM SVTVSAPKPA LGNPGRAPEN SEAQEPENDQ EPLPGLEEKP 800
    PGVGTSEGVY LTQLPHPTPP LQTDCTRQSS PQERETVGPE LKSSSSESAD 850
    NCKAMKGKNP WPSDSSYPGP AAQGCVRDLS TVADRGALSE NGVIGEASPC 900
    GSEGKGLGSS GSEKLLCPRG RTLQETMPCT GQNAATPPST DPGLTGGTVS 950
    QFPPLYMPGL EYPNSAAHYH ISPGLQGVGP VMGGKSPASH PQHFPPRGFQ 1000
    SNHPHSGGFP RYRPPQGMRY SYHPPPQPSY HHYQRTPYYA CPQSFSDWQR 1050
    PLHPQGSPSG PPASQPPPPR SLFSDKNAMA SLQGCETLNA ALTSPTRMDA 1100
    VAAKVPNDGQ NPGPEEEKLD ESMERPESPK EFLDLDNHNA ATKRQSSLSA 1150
    SEYLYGTPPP LSSGMGFGSS AFPPHSVMLQ TGPPYTPQRP ASHFQPRAYS 1200
    SPVAALPPHH PGATQPNGLS QEGPIYRCQE EGLGHFQAVM MEQIGTRSGI 1250
    RGPFQEMYRP SGMQMHPVQS QASFPKTPTA ATSQEEVPPH KPPTLPLDQS 1300
    Length:1,300
    Mass (Da):143,050
    Last modified:November 3, 2009 - v2
    Checksum:i229A7470D4A7E821
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007666 Genomic DNA. No translation available.
    FO681548 Genomic DNA. No translation available.
    RefSeqiNP_001276975.1. NM_001290046.1.
    UniGeneiHs.231895.
    Hs.658723.

    Genome annotation databases

    EnsembliENST00000400585; ENSP00000383428; ENSG00000099954.
    GeneIDi27443.
    KEGGihsa:27443.
    UCSCiuc010gqv.1. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007666 Genomic DNA. No translation available.
    FO681548 Genomic DNA. No translation available.
    RefSeqi NP_001276975.1. NM_001290046.1.
    UniGenei Hs.231895.
    Hs.658723.

    3D structure databases

    ProteinModelPortali B7WPH3.
    SMRi B7WPH3. Positions 229-354.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000400585 ; ENSP00000383428 ; ENSG00000099954 .
    GeneIDi 27443.
    KEGGi hsa:27443.
    UCSCi uc010gqv.1. human.

    Organism-specific databases

    CTDi 27443.
    HGNCi HGNC:1840. CECR2.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000081808.
    HOVERGENi HBG081078.
    OrthoDBi EOG7ZGX27.

    Miscellaneous databases

    ChiTaRSi CECR2. human.
    GenomeRNAii 27443.
    NextBioi 35478674.

    Gene expression databases

    ArrayExpressi B7WPH3.
    Bgeei B7WPH3.

    Family and domain databases

    Gene3Di 1.20.920.10. 1 hit.
    InterProi IPR001487. Bromodomain.
    IPR018359. Bromodomain_CS.
    IPR029614. CECR2.
    [Graphical view ]
    PANTHERi PTHR22880:SF123. PTHR22880:SF123. 1 hit.
    Pfami PF00439. Bromodomain. 1 hit.
    [Graphical view ]
    PRINTSi PR00503. BROMODOMAIN.
    SMARTi SM00297. BROMO. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47370. SSF47370. 1 hit.
    PROSITEi PS00633. BROMODOMAIN_1. 1 hit.
    PS50014. BROMODOMAIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of human chromosome 22."
      Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
      , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
      Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB7WPH3_HUMAN
    AccessioniPrimary (citable) accession number: B7WPH3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 10, 2009
    Last sequence update: November 3, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3