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Protein
Submitted name:

Echinoderm microtubule associated protein like 3, isoform CRA_e

Gene

EML3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Echinoderm microtubule associated protein like 3, isoform CRA_eImported
Submitted name:
Echinoderm microtubule-associated protein-like 3Imported
Gene namesi
Name:EML3Imported
ORF Names:hCG_20389Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:26666. EML3.

PTM / Processingi

Proteomic databases

EPDiB7WPE2.
PeptideAtlasiB7WPE2.

Expressioni

Gene expression databases

BgeeiENSG00000149499.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000378254.

Structurei

3D structure databases

SMRiB7WPE2. Positions 11-49, 217-871.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini594 – 764171WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili16 – 4328Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, WD repeatSAAS annotation

Phylogenomic databases

eggNOGiKOG2106. Eukaryota.
ENOG410XNTQ. LUCA.
GeneTreeiENSGT00550000074369.
HOGENOMiHOG000294061.
HOVERGENiHBG051470.

Family and domain databases

Gene3Di2.130.10.10. 3 hits.
InterProiIPR005108. HELP.
IPR011047. Quinoprotein_ADH-like_supfam.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF03451. HELP. 1 hit.
PF00400. WD40. 4 hits.
[Graphical view]
SMARTiSM00320. WD40. 8 hits.
[Graphical view]
SUPFAMiSSF50998. SSF50998. 3 hits.
PROSITEiPS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7WPE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGAAGPGDG PAREALQSLS QRLRVQEQEM ELVKAALAEA LRLLRLQVPP
60 70 80 90 100
SSLQGSGTPA PPGDSSLAAP PGLPPTCTPS LVSRGTQTET EVELKSSPGP
110 120 130 140 150
PGLSNGPPAP QGASEEPSGT QSEGGGSSSS GAGSPGPPGI LRPLQPPQRA
160 170 180 190 200
DTPRRNSSSS SSPSERPRQK LSRKAISSAN LLVRSGSTES RGGKDPLSSP
210 220 230 240 250
GGPGSRRSNY NLEGISVKMF LRGRPITMYI PSGIRSLEEL PSGPPPETLS
260 270 280 290 300
LDWVYGYRGR DSRSNLFVLR SGEVVYFIAC VVVLYRPGGG PGGPGGGGQR
310 320 330 340 350
HYRGHTDCVR CLAVHPDGVR VASGQTAGVD KDGKPLQPVV HIWDSETLLK
360 370 380 390 400
LQEIGLGAFE RGVGALAFSA ADQGAFLCVV DDSNEHMLSV WDCSRGMKLA
410 420 430 440 450
EIKSTNDSVL AVGFNPRDSS CIVTSGKSHV HFWNWSGGVG VPGNGTLTRK
460 470 480 490 500
QGVFGKYKKP KFIPCFVFLP DGDILTGDSE GNILTWGRSP SDSKTPGRGG
510 520 530 540 550
AKETYGIVAQ AHAHEGSIFA LCLRRDGTVL SGGGRDRRLV QWGPGLVALQ
560 570 580 590 600
EAEIPEHFGA VRAIAEGLGS ELLVGTTKNA LLRGDLAQGF SPVIQGHTDE
610 620 630 640 650
LWGLCTHPSQ NRFLTCGHDR QLCLWDGESH ALAWSIDLKE TGLCADFHPS
660 670 680 690 700
GAVVAVGLNT GRWLVLDTET REIVSDVIDG NEQLSVVRYS PDGLYLAIGS
710 720 730 740 750
HDNVIYIYSV SSDGAKSSRF GRCMGHSSFI THLDWSKDGN FIMSNSGDYE
760 770 780 790 800
ILYWDVAGGC KQLKNRYESR DREWATYTCV LGFHVYGVWP DGSDGTDINS
810 820 830 840 850
LCRSHNERVV AVADDFCKVH LFQYPCARAK APSRMYGGHG SHVTSVRFTH
860 870 880 890
DDSHLVSLGG KDASIFQWRV LGAGGAGPAP ATPSRTPSLS PASSLDV
Length:897
Mass (Da):95,284
Last modified:February 10, 2009 - v1
Checksum:iC7F59521F47349A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001458 Genomic DNA. No translation available.
CH471076 Genomic DNA. Translation: EAW74038.1.
RefSeqiXP_005273935.1. XM_005273878.3.
UniGeneiHs.379785.

Genome annotation databases

EnsembliENST00000278845; ENSP00000278845; ENSG00000149499.
GeneIDi256364.
UCSCiuc001nts.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001458 Genomic DNA. No translation available.
CH471076 Genomic DNA. Translation: EAW74038.1.
RefSeqiXP_005273935.1. XM_005273878.3.
UniGeneiHs.379785.

3D structure databases

SMRiB7WPE2. Positions 11-49, 217-871.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000378254.

Proteomic databases

EPDiB7WPE2.
PeptideAtlasiB7WPE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000278845; ENSP00000278845; ENSG00000149499.
GeneIDi256364.
UCSCiuc001nts.2. human.

Organism-specific databases

CTDi256364.
HGNCiHGNC:26666. EML3.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2106. Eukaryota.
ENOG410XNTQ. LUCA.
GeneTreeiENSGT00550000074369.
HOGENOMiHOG000294061.
HOVERGENiHBG051470.

Miscellaneous databases

ChiTaRSiEML3. human.
GenomeRNAii256364.

Gene expression databases

BgeeiENSG00000149499.

Family and domain databases

Gene3Di2.130.10.10. 3 hits.
InterProiIPR005108. HELP.
IPR011047. Quinoprotein_ADH-like_supfam.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF03451. HELP. 1 hit.
PF00400. WD40. 4 hits.
[Graphical view]
SMARTiSM00320. WD40. 8 hits.
[Graphical view]
SUPFAMiSSF50998. SSF50998. 3 hits.
PROSITEiPS50082. WD_REPEATS_2. 3 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB7WPE2_HUMAN
AccessioniPrimary (citable) accession number: B7WPE2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: September 7, 2016
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.