ALB

Functionⁱ

GO - Biological processⁱ

transport Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Serum albuminImported
Gene namesⁱ	Name:ALBImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 4

Organism-specific databases

HGNCⁱ

HGNC:399. ALB.

Subcellular locationⁱ

Secreted
PROSITE-ProRule annotation
Automatic assertion according to rulesⁱ
- PROSITE-ProRule:PRU00769

GO - Cellular componentⁱ

endoplasmic reticulum Source: HPA
extracellular space Source: InterPro
Golgi apparatus Source: HPA

Complete GO annotation...

Keywords - Cellular componentⁱ

SecretedPROSITE-ProRule annotation

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000163631.

OpenTargetsⁱ

ENSG00000163631.

Protein family/group databases

Allergomeⁱ	763. Hom s HSA.

Allergomeⁱ

763. Hom s HSA.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 18	Sequence analysisAdd BLAST		18
ChainⁱPRO_5002863313	19 – 494	Sequence analysisAdd BLAST		476

Amino acid modifications

Feature key	Position(s)	DescriptionActions
Disulfide bondⁱ	77 ↔ 86	PROSITE-ProRule annotation
Disulfide bondⁱ	109 ↔ 155	PROSITE-ProRule annotation
Disulfide bondⁱ	154 ↔ 162	PROSITE-ProRule annotation
Disulfide bondⁱ	187 ↔ 198	PROSITE-ProRule annotation
Disulfide bondⁱ	225 ↔ 270	PROSITE-ProRule annotation
Disulfide bondⁱ	269 ↔ 278	PROSITE-ProRule annotation
Disulfide bondⁱ	301 ↔ 347	PROSITE-ProRule annotation
Disulfide bondⁱ	346 ↔ 354	PROSITE-ProRule annotation
Disulfide bondⁱ	385 ↔ 396	PROSITE-ProRule annotation
Disulfide bondⁱ	423 ↔ 468	PROSITE-ProRule annotation
Disulfide bondⁱ	467 ↔ 476	PROSITE-ProRule annotation

Keywords - PTMⁱ

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PaxDbⁱ	B7WNR0.
PeptideAtlas More...PeptideAtlasⁱ	B7WNR0.
PRIDEⁱ	B7WNR0.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000163631.
ExpressionAtlasⁱ	B7WNR0. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000295897.

STRINGⁱ

9606.ENSP00000295897.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	B7WNR0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	1 – 95	AlbuminInterPro annotationAdd BLAST	95
Domainⁱ	96 – 288	AlbuminInterPro annotationAdd BLAST	193
Domainⁱ	289 – 486	AlbuminInterPro annotationAdd BLAST	198

Sequence similaritiesⁱ

Belongs to the ALB/AFP/VDB family.PROSITE-ProRule annotation

Keywords - Domainⁱ

SignalSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IIRZ. Eukaryota. ENOG410Z40H. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000000113.
HOGENOMⁱ	HOG000293137.
HOVERGENⁱ	HBG004207.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00015. ALBUMIN. 2 hits.
InterProⁱ	View protein in InterPro IPR000264. ALB/AFP/VDB. IPR020858. Serum_albumin-like. IPR020857. Serum_albumin_CS. IPR014760. Serum_albumin_N.
PANTHERⁱ	PTHR11385. PTHR11385. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00273. Serum_albumin. 3 hits.
PRINTSⁱ	PR00802. SERUMALBUMIN.
SMARTⁱ	View protein in SMART SM00103. ALBUMIN. 2 hits.
SUPFAMⁱ	SSF48552. SSF48552. 3 hits.
PROSITEⁱ	View protein in PROSITE PS00212. ALBUMIN_1. 2 hits. PS51438. ALBUMIN_2. 3 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

B7WNR0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKWVTFISLL FLFSSAYSRG VFRRDAHKSE VAHRFKDLGE ENFKALYLYE 
        60         70         80         90        100
IARRHPYFYA PELLFFAKRY KAAFTECCQA ADKAACLLPK LDELRDEGKA 
       110        120        130        140        150
SSAKQRLKCA SLQKFGERAF KAWAVARLSQ RFPKAEFAEV SKLVTDLTKV 
       160        170        180        190        200
HTECCHGDLL ECADDRADLA KYICENQDSI SSKLKECCEK PLLEKSHCIA 
       210        220        230        240        250
EVENDEMPAD LPSLAADFVE SKDVCKNYAE AKDVFLGMFL YEYARRHPDY 
       260        270        280        290        300
SVVLLLRLAK TYETTLEKCC AAADPHECYA KVFDEFKPLV EEPQNLIKQN 
       310        320        330        340        350
CELFEQLGEY KFQNALLVRY TKKVPQVSTP TLVEVSRNLG KVGSKCCKHP 
       360        370        380        390        400
EAKRMPCAED YLSVVLNQLC VLHEKTPVSD RVTKCCTESL VNRRPCFSAL 
       410        420        430        440        450
EVDETYVPKE FNAETFTFHA DICTLSEKER QIKKQTALVE LVKHKPKATK 
       460        470        480        490 
EQLKAVMDDF AAFVEKCCKA DDKETCFAEE GKKLVAASQA ALGL

Length:494

Mass (Da):56,212

Last modified:February 10, 2009 - v1

Checksum:ⁱ2DDA575EC942D671

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC108157 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC108157 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000401494; ENSP00000384695; ENSG00000163631.
UCSC genome browser More...UCSCⁱ	uc062xfw.1. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC108157 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC108157 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	B7WNR0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000295897.

STRINGⁱ

9606.ENSP00000295897.

Protein family/group databases

Allergomeⁱ	763. Hom s HSA.

Allergomeⁱ

763. Hom s HSA.

Proteomic databases

PaxDbⁱ	B7WNR0.
PeptideAtlas More...PeptideAtlasⁱ	B7WNR0.
PRIDEⁱ	B7WNR0.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000401494; ENSP00000384695; ENSG00000163631.
UCSC genome browser More...UCSCⁱ	uc062xfw.1. human.

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:399. ALB.
Open Targets More...OpenTargetsⁱ	ENSG00000163631.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IIRZ. Eukaryota. ENOG410Z40H. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000000113.
HOGENOMⁱ	HOG000293137.
HOVERGENⁱ	HBG004207.

Miscellaneous databases

ChiTaRSⁱ	ALB. human.

ChiTaRSⁱ

ALB. human.

Gene expression databases

Bgeeⁱ	ENSG00000163631.
ExpressionAtlasⁱ	B7WNR0. baseline and differential.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00015. ALBUMIN. 2 hits.
InterProⁱ	View protein in InterPro IPR000264. ALB/AFP/VDB. IPR020858. Serum_albumin-like. IPR020857. Serum_albumin_CS. IPR014760. Serum_albumin_N.
PANTHERⁱ	PTHR11385. PTHR11385. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00273. Serum_albumin. 3 hits.
PRINTSⁱ	PR00802. SERUMALBUMIN.
SMARTⁱ	View protein in SMART SM00103. ALBUMIN. 2 hits.
SUPFAMⁱ	SSF48552. SSF48552. 3 hits.
PROSITEⁱ	View protein in PROSITE PS00212. ALBUMIN_1. 2 hits. PS51438. ALBUMIN_2. 3 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B7WNR0_HUMAN
Accessionⁱ	B7WNR0Primary (citable) accession number: B7WNR0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 10, 2009
	Last sequence update:	February 10, 2009
	Last modified:	June 7, 2017
	This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B7WNR0 (B7WNR0_HUMAN)

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Serum albumin

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Protein family/group databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ