Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Serum albumin

Gene

ALB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Serum albuminImported
Gene namesi
Name:ALBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:399. ALB.

Subcellular locationi

  • Secreted PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedPROSITE-ProRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163631.

Protein family/group databases

Allergomei763. Hom s HSA.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500286331319 – 494Sequence analysisAdd BLAST476

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi77 ↔ 86PROSITE-ProRule annotation
Disulfide bondi109 ↔ 155PROSITE-ProRule annotation
Disulfide bondi154 ↔ 162PROSITE-ProRule annotation
Disulfide bondi187 ↔ 198PROSITE-ProRule annotation
Disulfide bondi225 ↔ 270PROSITE-ProRule annotation
Disulfide bondi269 ↔ 278PROSITE-ProRule annotation
Disulfide bondi301 ↔ 347PROSITE-ProRule annotation
Disulfide bondi346 ↔ 354PROSITE-ProRule annotation
Disulfide bondi385 ↔ 396PROSITE-ProRule annotation
Disulfide bondi423 ↔ 468PROSITE-ProRule annotation
Disulfide bondi467 ↔ 476PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

PaxDbiB7WNR0.
PeptideAtlasiB7WNR0.
PRIDEiB7WNR0.

Expressioni

Gene expression databases

BgeeiENSG00000163631.
ExpressionAtlasiB7WNR0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000295897.

Structurei

3D structure databases

ProteinModelPortaliB7WNR0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 95AlbuminInterPro annotationAdd BLAST95
Domaini96 – 288AlbuminInterPro annotationAdd BLAST193
Domaini289 – 486AlbuminInterPro annotationAdd BLAST198

Sequence similaritiesi

Belongs to the ALB/AFP/VDB family.PROSITE-ProRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IIRZ. Eukaryota.
ENOG410Z40H. LUCA.
GeneTreeiENSGT00390000000113.
HOGENOMiHOG000293137.
HOVERGENiHBG004207.

Family and domain databases

CDDicd00015. ALBUMIN. 2 hits.
InterProiView protein in InterPro
IPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
PANTHERiPTHR11385. PTHR11385. 1 hit.
PfamiView protein in Pfam
PF00273. Serum_albumin. 3 hits.
PRINTSiPR00802. SERUMALBUMIN.
SMARTiView protein in SMART
SM00103. ALBUMIN. 2 hits.
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiView protein in PROSITE
PS00212. ALBUMIN_1. 2 hits.
PS51438. ALBUMIN_2. 3 hits.

Sequencei

Sequence statusi: Complete.

B7WNR0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKWVTFISLL FLFSSAYSRG VFRRDAHKSE VAHRFKDLGE ENFKALYLYE
60 70 80 90 100
IARRHPYFYA PELLFFAKRY KAAFTECCQA ADKAACLLPK LDELRDEGKA
110 120 130 140 150
SSAKQRLKCA SLQKFGERAF KAWAVARLSQ RFPKAEFAEV SKLVTDLTKV
160 170 180 190 200
HTECCHGDLL ECADDRADLA KYICENQDSI SSKLKECCEK PLLEKSHCIA
210 220 230 240 250
EVENDEMPAD LPSLAADFVE SKDVCKNYAE AKDVFLGMFL YEYARRHPDY
260 270 280 290 300
SVVLLLRLAK TYETTLEKCC AAADPHECYA KVFDEFKPLV EEPQNLIKQN
310 320 330 340 350
CELFEQLGEY KFQNALLVRY TKKVPQVSTP TLVEVSRNLG KVGSKCCKHP
360 370 380 390 400
EAKRMPCAED YLSVVLNQLC VLHEKTPVSD RVTKCCTESL VNRRPCFSAL
410 420 430 440 450
EVDETYVPKE FNAETFTFHA DICTLSEKER QIKKQTALVE LVKHKPKATK
460 470 480 490
EQLKAVMDDF AAFVEKCCKA DDKETCFAEE GKKLVAASQA ALGL
Length:494
Mass (Da):56,212
Last modified:February 10, 2009 - v1
Checksum:i2DDA575EC942D671
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108157 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000401494; ENSP00000384695; ENSG00000163631.
UCSCiuc062xfw.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108157 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliB7WNR0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000295897.

Protein family/group databases

Allergomei763. Hom s HSA.

Proteomic databases

PaxDbiB7WNR0.
PeptideAtlasiB7WNR0.
PRIDEiB7WNR0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000401494; ENSP00000384695; ENSG00000163631.
UCSCiuc062xfw.1. human.

Organism-specific databases

HGNCiHGNC:399. ALB.
OpenTargetsiENSG00000163631.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IIRZ. Eukaryota.
ENOG410Z40H. LUCA.
GeneTreeiENSGT00390000000113.
HOGENOMiHOG000293137.
HOVERGENiHBG004207.

Miscellaneous databases

ChiTaRSiALB. human.

Gene expression databases

BgeeiENSG00000163631.
ExpressionAtlasiB7WNR0. baseline and differential.

Family and domain databases

CDDicd00015. ALBUMIN. 2 hits.
InterProiView protein in InterPro
IPR000264. ALB/AFP/VDB.
IPR020858. Serum_albumin-like.
IPR020857. Serum_albumin_CS.
IPR014760. Serum_albumin_N.
PANTHERiPTHR11385. PTHR11385. 1 hit.
PfamiView protein in Pfam
PF00273. Serum_albumin. 3 hits.
PRINTSiPR00802. SERUMALBUMIN.
SMARTiView protein in SMART
SM00103. ALBUMIN. 2 hits.
SUPFAMiSSF48552. SSF48552. 3 hits.
PROSITEiView protein in PROSITE
PS00212. ALBUMIN_1. 2 hits.
PS51438. ALBUMIN_2. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiB7WNR0_HUMAN
AccessioniPrimary (citable) accession number: B7WNR0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 10, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.