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Protein

Ribosomal RNA small subunit methyltransferase F

Gene

rsmF

Organism
Vibrio tasmaniensis (strain LGP32) (Vibrio splendidus (strain Mel32))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(1407) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1407) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei147S-adenosyl-L-methionineUniRule annotation1
Binding sitei174S-adenosyl-L-methionineUniRule annotation1
Binding sitei192S-adenosyl-L-methionineUniRule annotation1
Active sitei245NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, RNA-binding, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase FUniRule annotation (EC:2.1.1.178UniRule annotation)
Alternative name(s):
16S rRNA m5C1407 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RsmFUniRule annotation
Gene namesi
Name:rsmFUniRule annotation
Ordered Locus Names:VS_1411
OrganismiVibrio tasmaniensis (strain LGP32) (Vibrio splendidus (strain Mel32))
Taxonomic identifieri575788 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000009100 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001856471 – 473Ribosomal RNA small subunit methyltransferase FAdd BLAST473

Interactioni

Protein-protein interaction databases

STRINGi575788.VS_1411.

Structurei

3D structure databases

ProteinModelPortaliB7VNJ8.
SMRiB7VNJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni123 – 129S-adenosyl-L-methionine bindingUniRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
COG3270. LUCA.
HOGENOMiHOG000218115.
KOiK11392.
OMAiDPLFHAG.
OrthoDBiPOG091H02E2.

Family and domain databases

HAMAPiMF_01579. 16SrRNA_methyltr_F. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR031341. Methyltr_RsmF_N.
IPR001678. MeTrfase_RsmB/NOP2.
IPR027391. Nol1_Nop2_Fmu_2.
IPR011023. Nop2p.
IPR023267. RCMT.
IPR023545. rRNA_ssu_MeTfrase_F.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF17125. Methyltr_RsmF_N. 1 hit.
PF13636. Methyltranf_PUA. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00446. nop2p. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

B7VNJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHANVYIPEE FLTHIESIMP SHLDMASFVA SCQKPLRKSI RVNTLKISVE
60 70 80 90 100
DFLVRAKEKG WELEPVPWCE TGFWITADES EAPLGNTAEH MSGLFYIQEA
110 120 130 140 150
SSMMPPSALF QGEADYQAVL DTAAAPGSKT TQIAALMNNR GVLVANEYAA
160 170 180 190 200
SRVKVLHANI ERCGVRNAAL SNFDGRVFGG WLPEQFDAVL LDAPCSGEGT
210 220 230 240 250
IRKDADAMKN WTYQSVVDIA DTQKDLIESA FHALKPNGVL VYSTCTLSTE
260 270 280 290 300
ENQQVCHHLK ETFGDAVEFE SLESLFDNAK ATTTEEGFLH IFPQVYDSEG
310 320 330 340 350
FFVARIRKLA SVTPPEVKKR LGKFPFEKAS KKAQQEVAEQ LLGALDIELP
360 370 380 390 400
SDTQVWIRDK DVWLFPEALE PMIGEFRFSR MGIKIAETHK KGYRWQHQVA
410 420 430 440 450
TTLATGNEAN IVDLSIEDAR EWFMGRDVRP EGLSGEGEVL VKYNGAIIGL
460 470
GKWVGNRVKN GLPRELVRDK NLF
Length:473
Mass (Da):52,777
Last modified:February 10, 2009 - v1
Checksum:i9267E39DFE6C41F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM954972 Genomic DNA. Translation: CAV18574.1.
RefSeqiWP_012603876.1. NC_011753.2.

Genome annotation databases

EnsemblBacteriaiCAV18574; CAV18574; VS_1411.
GeneIDi7160984.
KEGGivsp:VS_1411.
PATRICifig|575788.5.peg.2717.

Similar proteinsi

Entry informationi

Entry nameiRSMF_VIBTL
AccessioniPrimary (citable) accession number: B7VNJ8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: June 7, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome