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B7VKR3

- GLSA_VIBSL

UniProt

B7VKR3 - GLSA_VIBSL

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Protein
Glutaminase
Gene
glsA, VS_2690
Organism
Vibrio splendidus (strain LGP32) (Vibrio splendidus (strain Mel32))
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei115 – 1151Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciVSPL575788:GH64-2647-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:VS_2690
OrganismiVibrio splendidus (strain LGP32) (Vibrio splendidus (strain Mel32))
Taxonomic identifieri575788 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000009100: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotation
PRO_1000132912Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi575788.VS_2690.

Structurei

3D structure databases

ProteinModelPortaliB7VKR3.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiMSIAVWS.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B7VKR3-1 [UniParc]FASTAAdd to Basket

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MKPTQAILAE ILDEVRPLIG QGKVADYIPA LARVSNQKLA IAVYTNEGEV    50
IQAGDADEAF SVQSISKALS LTLAMVLYKP EEIWQRVGKE PSGQAFNSMI 100
QLEMEHGIPR NPFINAGAIV VADLLQSRLS APRHRLLEFV RQLSGDTHIV 150
YDKVVAASEM MHSDRNAAIA YLMRSFGNFE NDVIPVLNNY FHACALKMTC 200
VDLAKTFSYL ANKGVSVQTK KEIITPVQTK QLNALLATCG LYDGAGEFAY 250
RVGMPGKSGV GGGIIAIVPG EMTIAVWSPE LDASGNSLAG TQALELLSER 300
IGRSIF 306
Length:306
Mass (Da):33,112
Last modified:February 10, 2009 - v1
Checksum:i11B1319A6376E762
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM954972 Genomic DNA. Translation: CAV19955.1.
RefSeqiYP_002418257.1. NC_011753.2.

Genome annotation databases

EnsemblBacteriaiCAV19955; CAV19955; VS_2690.
GeneIDi7162205.
KEGGivsp:VS_2690.
PATRICi20155942. VBIVibSpl48387_3932.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM954972 Genomic DNA. Translation: CAV19955.1 .
RefSeqi YP_002418257.1. NC_011753.2.

3D structure databases

ProteinModelPortali B7VKR3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 575788.VS_2690.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAV19955 ; CAV19955 ; VS_2690 .
GeneIDi 7162205.
KEGGi vsp:VS_2690.
PATRICi 20155942. VBIVibSpl48387_3932.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi MSIAVWS.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci VSPL575788:GH64-2647-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Vibrio splendidus str. LGP32 complete genome."
    Mazel D., Le Roux F.
    Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LGP32.

Entry informationi

Entry nameiGLSA_VIBSL
AccessioniPrimary (citable) accession number: B7VKR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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