B7VJI1 (GLMM_VIBSL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	VS_2488

Organism

Vibrio splendidus (strain LGP32) (Vibrio splendidus (strain Mel32)) [Complete proteome] [HAMAP]

Taxonomic identifier

575788 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio › Vibrio splendidus

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_1000185395
Sites
	Active site	103	1	Phosphoserine intermediate By similarity
	Metal binding	103	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	103	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7VJI1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 628E852BB714F8A2	FASTA	446	47,600
	10 20 30 40 50 60 MSEKRRYFGT DGVRGKVGQY PITPDFVLKL GWAAGRVLAK QGTKKVIIGK DTRISGYMLE 70 80 90 100 110 120 SALEAGLAAA GLQATFTGPM PTPAVAYLTQ TFRAEAGIVI SASHNPYYDN GIKFFSSEGT 130 140 150 160 170 180 KLSDEIELAI EAELDKDIEC VESSELGKAV RLNDAAGRYI EFCKSTFPHK MTLAGMKIVV 190 200 210 220 230 240 DCAHGATYHI APAVFKELGA EVVAIGVEPN GTNINHEVGA TDVRALQAKV VEEKAALGLG 250 260 270 280 290 300 FDGDGDRIIM VDELGNKVDG DQIAYIIARD ALRRGELKGG VVGTLMTNLG MENGLKQLGI 310 320 330 340 350 360 PFVRAAVGDR YVMEQLLAKG WKIGAENSGH VILLDKVTTG DAIVAALQVL ASVVDSEMTL 370 380 390 400 410 420 NELSQGMTLY PQVLENVRFS GDSNPLEAEA VKAAVIEVET ELGEKGRVLL RKSGTEPLLR 430 440 VMVEGEDAEL VQSSALKIAD AVKANC

References

[1]	"Vibrio splendidus str. LGP32 complete genome." Mazel D., Le Roux F. Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LGP32.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM954972 Genomic DNA. Translation: CAV19645.1.
RefSeq	YP_002418070.1. NC_011753.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	575788.VS_2488.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAV19645; CAV19645; VS_2488.
GeneID	7162023.
KEGG	vsp:VS_2488.
PATRIC	20155550. VBIVibSpl48387_3746.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
OMA	TLMSNMS.
ProtClustDB	PRK10887.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_VIBSL

Accession

Primary (citable) accession number: B7VJI1

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	February 10, 2009
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program