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B7VIW0 (UPPP_VIBSL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:VS_0406
OrganismVibrio splendidus (strain LGP32) (Vibrio splendidus (strain Mel32)) [Complete proteome] [HAMAP]
Taxonomic identifier575788 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 267267Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_1000148837

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane144 – 16421Helical; Potential
Transmembrane189 – 20921Helical; Potential
Transmembrane218 – 23821Helical; Potential
Transmembrane246 – 26621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
B7VIW0 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: E1195690BAE89804

FASTA26729,309
        10         20         30         40         50         60 
MSYFEAFMLA LVQGFTEFLP ISSSAHLILP SAVLGWEDQG LAFDVAVHVG TLAAVVIYFR 

        70         80         90        100        110        120 
KEVVSLLSAF FGSVFKGDRS KEAKLAWMII LATIPACIFG LLMKDIVELY LRSAWVIATT 

       130        140        150        160        170        180 
TIIFGLLLWW VDKNSSLRDD EYQAGWKKAL FIGLAQAMAI IPGTSRSGAT ITAALYLGFT 

       190        200        210        220        230        240 
REAAARFSFL MSIPIITLAG GYLGLKLVTS GDPIHVGTLL TGIVVSFISA YICIHFFLKL 

       250        260 
ISRMGMTPFV IYRLILGFGL FAFLMMQ 

« Hide

References

[1]"Vibrio splendidus str. LGP32 complete genome."
Mazel D., Le Roux F.
Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LGP32.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM954972 Genomic DNA. Translation: CAV17414.1.
RefSeqYP_002416064.1. NC_011753.2.

3D structure databases

ProteinModelPortalB7VIW0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING575788.VS_0406.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAV17414; CAV17414; VS_0406.
GeneID7160042.
KEGGvsp:VS_0406.
PATRIC20151514. VBIVibSpl48387_1771.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAMENIGWK.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycVSPL575788:GH64-388-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_VIBSL
AccessionPrimary (citable) accession number: B7VIW0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families