B7VH13 (B7VH13_VIBSL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dethiobiotin synthetase EMBL CAV19213.1

Gene names

Ordered Locus Names:

VS_2037

Organism

Vibrio splendidus (strain LGP32) (Vibrio splendidus (strain Mel32)) [Complete proteome] [HAMAP]

Taxonomic identifier

575788 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7VH13 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 6EA1C3EC54EF4EE4	FASTA	234	25,193
	10 20 30 40 50 60 MFRGYSIMID ALFIAGTDTE VGKTVVSKAI LQALAAQDLS TIGYKPVAAG CEQYPEGLRN 70 80 90 100 110 120 SDALHLQEAA TQDVAYEDVN PYALLLPSSP HIAAKHDGVV IDETVLSAKL AEHKQNSDIV 130 140 150 160 170 180 LVEGAGGWRV PVSDEEYLSS WVKKEQLPVV LTVGIKLGCL SHALLTAEVI RADGLNLVGW 190 200 210 220 230 VANRINPGTE HYAEIIAMLE DKLGAPKLGE IPYVPRAKSK NIGKYIDVQP LLAL

References

[1]	"Vibrio splendidus str. LGP32 complete genome." Mazel D., Le Roux F. Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM954972 Genomic DNA. Translation: CAV19213.1.
RefSeq	YP_002417638.1. NC_011753.2.
3D structure databases
ProteinModelPortal	B7VH13.
ModBase	Search...
Protein-protein interaction databases
STRING	B7VH13.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7161592.
GenomeReviews	Gene locus VS_2037 in contig FM954972_GR.
KEGG	vsp:VS_2037.
PATRIC	20154669. VBIVibSpl48387_3315.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG650065.
OMA	ALAAYWQ.
ProtClustDB	PRK00090.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
KO	K01935.
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7VH13_VIBSL

Accession

Primary (citable) accession number: B7VH13

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)