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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Pseudomonas aeruginosa (strain LESB58)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei68L-glutamineUniRule annotation1
Binding sitei213L-glutamineUniRule annotation1
Binding sitei232ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi36 – 38ATPUniRule annotation3
Nucleotide bindingi42 – 48ATPUniRule annotation7
Nucleotide bindingi262 – 263ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:PLES_35351
OrganismiPseudomonas aeruginosa (strain LESB58)
Taxonomic identifieri557722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001991021 – 556Glutamine--tRNA ligaseAdd BLAST556

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7VB85
SMRiB7VB85
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 45"HIGH" regionUniRule annotationAdd BLAST11
Motifi269 – 273"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000259232
KOiK01886
OMAiVTHSICT

Family and domain databases

Gene3Di1.10.1160.101 hit
2.40.240.103 hits
3.40.50.6202 hits
HAMAPiMF_00126 Gln_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR004514 Gln-tRNA-synth
IPR022861 Gln_tRNA_ligase_bac
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020061 Glu_tRNA_lig_a-bdl
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 1 hit
PF03950 tRNA-synt_1c_C, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B7VB85-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKPETTAAP NFLRQIVQAD LDAGKHAKIV TRFPPEPNGY LHIGHAKSIC
60 70 80 90 100
LNFGLAQEFA GDCHLRFDDT NPAKEDQEYI DAIEADIKWL GFQWSGEVCY
110 120 130 140 150
ASNYFDQLHA WAIELIKAGK AFVCDLGPEE MREYRGTLTE PGRNSPYRDR
160 170 180 190 200
SVEENLDLFA RMKAGEFPDG ARSLRAKIDM GSPNMNLRDP ILYRIRHAHH
210 220 230 240 250
HQTGDKWCIY PSYDFTHGQS DAIEGITHSI CTLEFEDHRP LYEWFLANLP
260 270 280 290 300
VPAQPRQYEF SRLNLNYTVT SKRKLKQLVD EGHVSGWDDP RMSTLSGYRR
310 320 330 340 350
RGYTPESIRN FCEMIGVNRA SGVVDIGMLE FSIRDHLDAT APRAMCVLKP
360 370 380 390 400
LKVVITNYPE GQVENLELPR HPKEDMGVRV LPFGRELFID AGDFEEVPPA
410 420 430 440 450
GYKRLIPGGE VRLRGSYVIR ADEAIKDADG NIVELRCSYD PDTLGKNPEG
460 470 480 490 500
RKVKGVIHWV PAEGSVECEV RLYDRLFRSA NPEKAEEGGS FLDNINADSL
510 520 530 540 550
QVLTGCRAEP SLGQANPEDR FQFEREGYFV ADLKDSRPGK PVFNRTVTLR

DSWGQG
Length:556
Mass (Da):62,957
Last modified:February 10, 2009 - v1
Checksum:i2851975F982926F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM209186 Genomic DNA Translation: CAW28262.1
RefSeqiWP_003139945.1, NC_011770.1

Genome annotation databases

EnsemblBacteriaiCAW28262; CAW28262; PLES_35351
KEGGipag:PLES_35351

Similar proteinsi

Entry informationi

Entry nameiSYQ_PSEA8
AccessioniPrimary (citable) accession number: B7VB85
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: February 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program