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B7V9H3 (GLK_PSEA8) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:PLES_18751
OrganismPseudomonas aeruginosa (strain LESB58) [Complete proteome] [HAMAP]
Taxonomic identifier557722 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331Glucokinase HAMAP-Rule MF_00524
PRO_1000127714

Regions

Nucleotide binding16 – 216ATP Potential

Sequences

Sequence LengthMass (Da)Tools
B7V9H3 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 321718790B5130D1

FASTA33134,606
        10         20         30         40         50         60 
MNNDNKRSAG GLGLVGDIGG TNARFALWRG QRLESIEVLA CADYPRPELA VRDYLARIGE 

        70         80         90        100        110        120 
SVANIDSVCL ACAGPVGAAD FRFTNNHWVI NRAAFREELG LDHLLLVNDF STMAWAASRL 

       130        140        150        160        170        180 
GADELVQVRA GSAQADRARL IIGPGTGLGV GSLLPLGGGR WEVLPCEGGH VDLPVTSPRD 

       190        200        210        220        230        240 
FALWQGLQAR YGHVSAERAL SGNGLLALYE ISCALDGVAV RASSAAEVGA LAMAGDAQAD 

       250        260        270        280        290        300 
AVLEHFFLWL ARVAGNAVLT VGALGGVYIT GGIVPRFLER FIASGFAEAF ASRGKTSGAY 

       310        320        330 
LQDVPVWVMT AEHPGLLGAG VALQQALDAE G 

« Hide

References

[1]"Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa."
Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C.
Genome Res. 19:12-23(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LESB58.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM209186 Genomic DNA. Translation: CAW26603.1.
RefSeqYP_002439479.1. NC_011770.1.

3D structure databases

ProteinModelPortalB7V9H3.
SMRB7V9H3. Positions 13-327.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING557722.PLES_18751.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAW26603; CAW26603; PLES_18751.
GeneID7179867.
KEGGpag:PLES_18751.
PATRIC19813385. VBIPseAer113719_1948.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADWVEMTN.
OrthoDBEOG64BQ47.
ProtClustDBPRK00292.

Enzyme and pathway databases

BioCycPAER557722:GHJW-1898-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_PSEA8
AccessionPrimary (citable) accession number: B7V9H3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: April 16, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families