B7V8M1 (B7V8M1_PSEA8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Name:	gcvT2 EMBL CAW27579.1
Ordered Locus Names:	PLES_28521

Organism

Pseudomonas aeruginosa (strain LESB58) [Complete proteome] [HAMAP]

Taxonomic identifier

557722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	373 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. SAAS SAAS006223 RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase SAAS SAAS006223 RuleBase RU003981 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7V8M1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 2B0BB3352C9A7391	FASTA	373	39,912
	10 20 30 40 50 60 MTAETLAKTP LHALHLELGA KMVPFAGYDM PVQYPAGVLK EHLHTREQAG LFDVSHMGQI 70 80 90 100 110 120 RLVGADAALA LESLVPVDIL DLPVGQQRYA LFTDEQGGIL DDLMVANLGD CLLLVVNAAC 130 140 150 160 170 180 KHQDLAHLRR HLEDRCSVEP LFEERALLAL QGPAAVRVLE RLAPQVAQMT FMQFARVELL 190 200 210 220 230 240 GQDCYVSRSG YTGEDGYEIS VPAAHAEALA RRLLAEPEVA PIGLGARDSL RLEAGLCLYG 250 260 270 280 290 300 HDMDSATTPV EASLGWAISK ARRADGVRAG GFPGAERIFA QQAQGVASKR VGFLPQGRMP 310 320 330 340 350 360 VREGAEIVDA QGRAIGKVSS GGFGPSLNAP LAMGYVPSEL AGLGSEVTAM VRGKPVTLVV 370 SKMPFVAQRY YRG

References

[1]

"Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa." Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C. Genome Res. 19:12-23(2009) [PubMed: 19047519] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM209186 Genomic DNA. Translation: CAW27579.1.
RefSeq	YP_002440443.1. NC_011770.1.
3D structure databases
ProteinModelPortal	B7V8M1.
ModBase	Search...
Protein-protein interaction databases
STRING	B7V8M1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7180996.
GenomeReviews	Gene locus PLES_28521 in contig FM209186_GR.
KEGG	pag:PLES_28521.
PATRIC	19815386. VBIPseAer113719_2925.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG299834.
OMA	GPTLNAP.
ProtClustDB	CLSK867274.
Family and domain databases
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view]
KO	K00605.
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. GcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7V8M1_PSEA8

Accession

Primary (citable) accession number: B7V8M1

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)