B7V3H7 (B7V3H7_PSEA8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
D-amino acid dehydrogenase small subunit 1 HAMAP MF_01202
EC=1.4.99.1 HAMAP MF_01202

Gene names

Name:	dadA1 HAMAP MF_01202
Ordered Locus Names:	PLES_54741

Organism

Pseudomonas aeruginosa (strain LESB58) [Complete proteome] [HAMAP]

Taxonomic identifier

557722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	416 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Oxidative deamination of D-amino acids By similarity. HAMAP MF_01202 SAAS SAAS023080
Catalytic activity	A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP MF_01202 SAAS SAAS023080
Cofactor	FAD By similarity. HAMAP MF_01202 SAAS SAAS023080
Pathway	Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP MF_01202
Subunit structure	Heterodimer of a small and a large subunit By similarity. HAMAP MF_01202 SAAS SAAS023080
Sequence similarities	Belongs to the DadA oxidoreductase family. HAMAP MF_01202

Ontologies

Keywords
Ligand	FAD HAMAP MF_01202 SAAS SAAS023080 Flavoprotein HAMAP MF_01202 SAAS SAAS023080
Molecular function	Oxidoreductase HAMAP MF_01202 SAAS SAAS023080
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	alanine catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	D-amino-acid dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	5 – 19	15	FAD By similarity HAMAP MF_01202

Sequences

	Sequence		Length	Mass (Da)
	B7V3H7 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 41FA893B3FD903B9	FASTA	416	44,787
	10 20 30 40 50 60 MAQRVCIIGA GVVGLATAYA LVREGFDVTL VEARERGGLE TSYANGGQLS YRYVAPLADS 70 80 90 100 110 120 GVPAQALGWL LRNDAPLRLR PRLDPAQWRW LLGFLAACRG SLNCRNAAHL LRLALLSQRT 130 140 150 160 170 180 LQAWREEDGL DGFDWRRNGK LVAFRQPASF ARARQGLADP SAQFVLSAAE CRELEPALSD 190 200 210 220 230 240 APFVGGIHTP DEEVADCHAF CVQLAERLQA SGHCRQLHGR RVTKIVEGGA AVRGVEVGGD 250 260 270 280 290 300 LIEADHVVLA AGYRSAELML PGLRLPLYPL KGYSLTLPVG AQHRAPDTSI TDYDRKIVYA 310 320 330 340 350 360 RIGERLRIAA MVDIVGFDPG LEPARLALLR QQARDTFPQG GDFDAAVEWA GMRPATPTGV 370 380 390 400 410 PLVGNGGYRN LWLNLGHGAL GFTLACGSGR LLAEQIGRRP PSIDTSGLLP RGALAG

References

[1]

"Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa." Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C. Genome Res. 19:12-23(2009) [PubMed: 19047519] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM209186 Genomic DNA. Translation: CAW30228.1.
RefSeq	YP_002443052.1. NC_011770.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7V3H7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7179188.
GenomeReviews	Gene locus PLES_54741 in contig FM209186_GR.
KEGG	pag:PLES_54741.
PATRIC	19820867. VBIPseAer113719_5627.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG729204.
OMA	AQWRWLL.
ProtClustDB	CLSK869108.
Family and domain databases
HAMAP	MF_01202. DadA. [Tree]
InterPro	IPR023080. D-aa_DH_ssu_DadA. IPR006076. FAD-dep_OxRdtase. [Graphical view]
KO	K00285.
Pfam	PF01266. DAO. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7V3H7_PSEA8

Accession

Primary (citable) accession number: B7V3H7

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)