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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pseudomonas aeruginosa (strain LESB58)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:PLES_54411
OrganismiPseudomonas aeruginosa (strain LESB58)
Taxonomic identifieri557722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001989271 – 587Arginine--tRNA ligaseAdd BLAST587

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliB7V3E4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B7V3E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDTIRQLIQ QALDQLTADG TLPAGLTPDI QVENTKDRSH GDFASNIAMM
60 70 80 90 100
LAKPAGMKPR DLAARLVEAI PAHEQLAKVE IAGPGFLNFF QDHVWLAASL
110 120 130 140 150
DRALADERLG VRKAGPAQRV VIDLSSPNLA KEMHVGHLRS TIIGDAVARV
160 170 180 190 200
LEFLGDTVIR QNHVGDWGTQ FGMLLAYLEE QPIDAEAELH DLEVFYRAAK
210 220 230 240 250
KRFDESPEFA DRARELVVKL QAGDPDCLRL WTRFNEISLS HCQKVYDRLG
260 270 280 290 300
VKLSMADVMG ESAYNDDLAQ VVADLTAKGL LTEDNGALCV FLEEFKNAEG
310 320 330 340 350
NPLPVIVQKA GGGYLYATTD LAAMRYRHNV LHADRVLYFV DQRQALHFQQ
360 370 380 390 400
VFEVARRAGF VPAGMELEHM GFGTMNGADG RPFKTRDGGT VKLIDLLEEA
410 420 430 440 450
ESRAYALVKE RNEQRAERGE EPFDEVQLRE IGRVVGIDSV KYADLSKHRT
460 470 480 490 500
SDYSFNFELM LSFEGNTAPY LLYACTRVAS VFRKLGQGRE QLGGKIVLEQ
510 520 530 540 550
PQELALAAQL AQFGDLINNV ALKGVPHLLC AYLYELAGLF SSFYEHCPIL
560 570 580
TAEDPAQKDS RLRLAALTGR TLEQGLELLG LKTLERM
Length:587
Mass (Da):65,213
Last modified:February 10, 2009 - v1
Checksum:i8053B18BC0587B62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM209186 Genomic DNA. Translation: CAW30195.1.
RefSeqiWP_012614630.1. NC_011770.1.

Genome annotation databases

EnsemblBacteriaiCAW30195; CAW30195; PLES_54411.
KEGGipag:PLES_54411.

Similar proteinsi

Entry informationi

Entry nameiSYR_PSEA8
AccessioniPrimary (citable) accession number: B7V3E4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: November 22, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families