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Protein

Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

Gene

mdcB

Organism
Pseudomonas aeruginosa (strain LESB58)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.UniRule annotation

Catalytic activityi

ATP + 3'-dephospho-CoA = 2'-(5-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPAER557722:GHJW-204-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthaseUniRule annotation (EC:2.4.2.52UniRule annotation)
Short name:
2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthaseUniRule annotation
Gene namesi
Name:mdcBUniRule annotation
Ordered Locus Names:PLES_02041
OrganismiPseudomonas aeruginosa (strain LESB58)
Taxonomic identifieri557722 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthasePRO_1000189588Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the CitG/MdcB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000258582.
KOiK13930.
OMAiQSWQRPA.

Family and domain databases

HAMAPiMF_01883. MdcB. 1 hit.
InterProiIPR002736. CitG.
IPR017555. TriPribosyl-deP-CoA_syn.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03132. malonate_mdcB. 1 hit.

Sequencei

Sequence statusi: Complete.

B7V2C0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAIANLAAT PCADLGECLA DLAVDALIDE AELSPKPALV DRRGNGAHAD
60 70 80 90 100
LHLGLMQASA LSLWPCFKEM ADAAQRHGRI DARLRGVLGQ LGRDGEAAML
110 120 130 140 150
RTTEGVNTHR GAIWALGLLV AAAALEPRRT QAGEVAARAG RIALLDDPAA
160 170 180 190 200
AIGDSHGERV RRRYGVGGAR EEARLGFPRA VRHGLPQLWR SREGGAGEQN
210 220 230 240 250
ARLDALLAIM SVLDDTCVLH RAGRVGLAVM QDGARAVLAA GGSASLAGRR
260 270 280 290
RLCELDRRLL ALNASPGGAA DLLAACLFLD RLPAVSGGWA GSL
Length:293
Mass (Da):30,562
Last modified:February 10, 2009 - v1
Checksum:iA2AE90BB2BD770EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM209186 Genomic DNA. Translation: CAW24931.1.
RefSeqiWP_012613463.1. NC_011770.1.

Genome annotation databases

EnsemblBacteriaiCAW24931; CAW24931; PLES_02041.
KEGGipag:PLES_02041.
PATRICi19809872. VBIPseAer113719_0210.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM209186 Genomic DNA. Translation: CAW24931.1.
RefSeqiWP_012613463.1. NC_011770.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAW24931; CAW24931; PLES_02041.
KEGGipag:PLES_02041.
PATRICi19809872. VBIPseAer113719_0210.

Phylogenomic databases

HOGENOMiHOG000258582.
KOiK13930.
OMAiQSWQRPA.

Enzyme and pathway databases

BioCyciPAER557722:GHJW-204-MONOMER.

Family and domain databases

HAMAPiMF_01883. MdcB. 1 hit.
InterProiIPR002736. CitG.
IPR017555. TriPribosyl-deP-CoA_syn.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03132. malonate_mdcB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMDCB_PSEA8
AccessioniPrimary (citable) accession number: B7V2C0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.