B7UYX4 (B7UYX4_PSEA8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Signal peptidase I RuleBase RU003993
EC=3.4.21.89 RuleBase RU003993

Gene names

Name:	lepB EMBL CAW29329.1
Ordered Locus Names:	PLES_45751

Organism

Pseudomonas aeruginosa (strain LESB58) [Complete proteome] [HAMAP]

Taxonomic identifier

557722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	284 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins. RuleBase RU003993
Sequence similarities	Belongs to the peptidase S26 family. RuleBase RU003989

Ontologies

Keywords
Molecular function	Hydrolase Protease RuleBase RU003988
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7UYX4 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: ACA143F48F90ED2C	FASTA	284	32,103
	10 20 30 40 50 60 MTLNFPLLLV IAVAVCGALA LVDLVLFAPR RRAAISSYEG QVNEPDPAVL EKLNKEPLLV 70 80 90 100 110 120 EYGKSFFPVL FIVLVLRSFL VEPFQIPSGS MKPTLEVGDF ILVNKFAYGI RLPVLDTKVI 130 140 150 160 170 180 PIGDPQRGDV MVFRYPSEPN INYIKRVVGL PGDTVRYTKE KRLYVNGELV AEKLVGEEPG 190 200 210 220 230 240 TLGSVTLYQE KLGQAEHLIR KEMSRYRIEP DRQWTIPAGH YFMMGDNRDN SNDSRYWNDP 250 260 270 280 KIPKDLLGMV PDRNIVGKAF AVWMSWPDPK MSNLPNFSRV GVIH

References

[1]

"Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa." Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C. Genome Res. 19:12-23(2009) [PubMed: 19047519] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM209186 Genomic DNA. Translation: CAW29329.1.
RefSeq	YP_002442158.1. NC_011770.1.
3D structure databases
ProteinModelPortal	B7UYX4.
ModBase	Search...
Protein-protein interaction databases
STRING	B7UYX4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7178570.
GenomeReviews	Gene locus PLES_45751 in contig FM209186_GR.
KEGG	pag:PLES_45751.
PATRIC	19818948. VBIPseAer113719_4692.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG596607.
OMA	RYPSDPN.
ProtClustDB	CLSK866103.
Family and domain databases
InterPro	IPR000223. Pept_S26A_signal_pept_1. IPR019758. Pept_S26A_signal_pept_1_CS. IPR019757. Pept_S26A_signal_pept_1_Lys-AS. IPR019756. Pept_S26A_signal_pept_1_Ser-AS. IPR019759. Peptidase_S24_S26. IPR015927. Peptidase_S24_S26A/B/C. IPR011056. Peptidase_S24_S26A/B/C_b-rbn. [Graphical view]
Gene3D	G3DSA:2.10.109.10. Pept_S24_S26_C. 2 hits.
KO	K03100.
Pfam	PF00717. Peptidase_S24. 1 hit. [Graphical view]
PRINTS	PR00727. LEADERPTASE.
SUPFAM	SSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMs	TIGR02227. Sigpep_I_bact. 1 hit.
PROSITE	PS00501. SPASE_I_1. 1 hit. PS00760. SPASE_I_2. 1 hit. PS00761. SPASE_I_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7UYX4_PSEA8

Accession

Primary (citable) accession number: B7UYX4

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)