B7UYP5 (B7UYP5_PSEA8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase 1 HAMAP MF_00212
EC=1.1.5.4 HAMAP MF_00212

Alternative name(s):
MQO 1 HAMAP MF_00212
Malate dehydrogenase [quinone] 1 HAMAP MF_00212

Gene names

Name:	mqoA EMBL CAW26336.1
Synonyms:	mqo1 HAMAP MF_00212
Ordered Locus Names:	PLES_16081

Organism

Pseudomonas aeruginosa (strain LESB58) [Complete proteome] [HAMAP]

Taxonomic identifier

557722 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212 SAAS SAAS006231
Cofactor	FAD By similarity. HAMAP MF_00212 SAAS SAAS006231
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212 SAAS SAAS006231
Sequence similarities	Belongs to the MQO family. HAMAP MF_00212

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle HAMAP MF_00212 SAAS SAAS006231
Ligand	FAD HAMAP MF_00212 SAAS SAAS006231 Flavoprotein HAMAP MF_00212 SAAS SAAS006231
Molecular function	Oxidoreductase HAMAP MF_00212 SAAS SAAS006231
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7UYP5 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 03E90117F88890B3	FASTA	523	57,210
	10 20 30 40 50 60 MKKILLMLLC VSVLGCSKNS VESEKPVDVL LIGGGIMSAT LGTYLNELEP GWTIEMVERL 70 80 90 100 110 120 DKVAEESSNG WNNAGTGHSA FCELNYTSEA ADGSMDISKA VAINENFEIS KQFWAYQVDR 130 140 150 160 170 180 KVLNDPKSFI NNVPHMSFVW GDDNVAFLKK RHAALQHSSL FRGMEYSEDP EQIKQWVPLV 190 200 210 220 230 240 MEGREPGQKI AATRMSIGTD VNFGEITRQL VGSLSAKDTF KLRLQHEVRD LKRNDDNTWT 250 260 270 280 290 300 VTMADLANGD KETSVKARFV FIGAGGGALK LLQMSGIPEA EGYAGFPVGG SFLATTNPDV 310 320 330 340 350 360 VKRHLAKVYG KASVGSPPMS VPHLDTRMID GKPVLLFGPF ATFSTKFLKN GSLWDLPGSV 370 380 390 400 410 420 TSGNIGPMFN AGIDNFDLSQ YLIGQLMLSQ DDRMASLREY FPEARDEDWK LVQAGQRVQI 430 440 450 460 470 480 IKKDAEKGGV LQFGTEVVTA ADGSVAALLG ASPGASTAAP IMLSVLEKAF KDKVATPEWQ 490 500 510 520 ARLKEIVPSY GRKLNNDIEL TNSTRAWSSE RLQLIHVPVQ PEA

References

[1]

"Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa." Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C. Genome Res. 19:12-23(2009) [PubMed: 19047519] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM209186 Genomic DNA. Translation: CAW26336.1.
RefSeq	YP_002439212.1. NC_011770.1.
3D structure databases
ProteinModelPortal	B7UYP5.
ModBase	Search...
Protein-protein interaction databases
STRING	B7UYP5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7176312.
GenomeReviews	Gene locus PLES_16081 in contig FM209186_GR.
KEGG	pag:PLES_16081.
PATRIC	19812816. VBIPseAer113719_1667.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289663.
OMA	ATFSTKY.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7UYP5_PSEA8

Accession

Primary (citable) accession number: B7UYP5

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)