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B7UY36 (B7UY36_PSEA8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:aruD EMBL CAW29173.1
Synonyms:astD HAMAP MF_01174
Ordered Locus Names:PLES_44181
OrganismPseudomonas aeruginosa (strain LESB58) [Complete proteome] [HAMAP]
Taxonomic identifier557722 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length488 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174 SAAS SAAS017649

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174 SAAS SAAS017649

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174 SAAS SAAS017649

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding222 – 2276NAD By similarity HAMAP MF_01174

Sites

Active site2451 By similarity HAMAP MF_01174
Active site2791 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
B7UY36 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: C656C459E4069A50

FASTA48851,564
        10         20         30         40         50         60 
MMSTHYIAGQ WLAGQGETLE SLDPVGQGVV WSGRGADATQ VDAAVRAARE AFPAWARRPL 

        70         80         90        100        110        120 
EQRIELLERF AATLKSRADE LARVIGEETG KPLWESATEV TSMVNKVAIS VQAFRERTGE 

       130        140        150        160        170        180 
KSGPLADATA VLRHKPHGVV AVFGPYNFPG HLPNGHIVPA LLAGNCVVFK PSELTPKVAE 

       190        200        210        220        230        240 
LTLKAWIQAG LPAGVLNLVQ GGRETGVALA AHRGLDGLFF TGSSRTGNLL HSQFGGQPQK 

       250        260        270        280        290        300 
ILALEMGGNN PLVVEEVADL DAAVYTIIQS AFISAGQRCT CARRLLVPQG AWGDALLARL 

       310        320        330        340        350        360 
VAVSATLRVG RFDEQPAPFM GAVISLSAAE HLLKAQEHLI GKGAQPLLAM TQPIDGAALL 

       370        380        390        400        410        420 
TPGILDVSAV AERPDEEFFG PLLQVIRYSD FAAAIREANA TQYGLAAGLL SDSRERFEQF 

       430        440        450        460        470        480 
LVESRAGIVN WNKQLTGAAS SAPFGGIGAS GNHRPSAYYA ADYCAYPVAS LESPSVSLPA 


TLTPGISL

« Hide

References

[1]"Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa."
Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C.
Genome Res. 19:12-23(2009) [PubMed: 19047519] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FM209186 Genomic DNA. Translation: CAW29173.1.
RefSeqYP_002442002.1. NC_011770.1.

3D structure databases

ProteinModelPortalB7UY36.
ModBaseSearch...

Protein-protein interaction databases

STRINGB7UY36.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7179636.
GenomeReviewsGene locus PLES_44181 in contig FM209186_GR.
KEGGpag:PLES_44181.
PATRIC19818664. VBIPseAer113719_4551.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG752218.
OMAMTQRDPR.
ProtClustDBPRK09457.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK06447.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7UY36_PSEA8
AccessionPrimary (citable) accession number: B7UY36
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info