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B7UV24

- LFTR_PSEA8

UniProt

B7UV24 - LFTR_PSEA8

Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Pseudomonas aeruginosa (strain LESB58)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

    Catalytic activityi

    L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
    L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

    GO - Molecular functioni

    1. leucyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciPAER557722:GHJW-2524-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
    Alternative name(s):
    L/F-transferaseUniRule annotation
    LeucyltransferaseUniRule annotation
    PhenyalanyltransferaseUniRule annotation
    Gene namesi
    Name:aatUniRule annotation
    Ordered Locus Names:PLES_24881
    OrganismiPseudomonas aeruginosa (strain LESB58)
    Taxonomic identifieri557722 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000001527: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 226226Leucyl/phenylalanyl-tRNA--protein transferasePRO_1000131938Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi557722.PLES_24881.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the L/F-transferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2360.
    HOGENOMiHOG000102325.
    KOiK00684.
    OMAiWSPDPRG.
    OrthoDBiEOG6WX4R3.

    Family and domain databases

    HAMAPiMF_00688. Leu_Phe_trans.
    InterProiIPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view]
    PfamiPF03588. Leu_Phe_trans. 1 hit.
    [Graphical view]
    SUPFAMiSSF55729. SSF55729. 1 hit.
    TIGRFAMsiTIGR00667. aat. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B7UV24-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLTWLSRTDF DFPPLDKALQ EPNGLLAAGG DLNPQRLVAA YRHGCFPWYQ    50
    DGQPILWWSP DPRTVLFPDE LHVSRSLAKC LRQQRFEVTF NRDFRAVIQA 100
    CAAPRDYADG TWITTPMQLA YQELHLRGIA HSVEVWQERQ LVGGLYGLAM 150
    GRLFFGESMF SRADNASKVG FVTLVRHLRD AGFVLIDCQM PTRHLHSLGA 200
    RAISRGEFAD YLQRYRDQPP TGDLDF 226
    Length:226
    Mass (Da):25,827
    Last modified:February 10, 2009 - v1
    Checksum:i009365579000C8A7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM209186 Genomic DNA. Translation: CAW27214.1.
    RefSeqiYP_002440088.1. NC_011770.1.

    Genome annotation databases

    EnsemblBacteriaiCAW27214; CAW27214; PLES_24881.
    GeneIDi7176977.
    KEGGipag:PLES_24881.
    PATRICi19814677. VBIPseAer113719_2578.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM209186 Genomic DNA. Translation: CAW27214.1 .
    RefSeqi YP_002440088.1. NC_011770.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 557722.PLES_24881.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAW27214 ; CAW27214 ; PLES_24881 .
    GeneIDi 7176977.
    KEGGi pag:PLES_24881.
    PATRICi 19814677. VBIPseAer113719_2578.

    Phylogenomic databases

    eggNOGi COG2360.
    HOGENOMi HOG000102325.
    KOi K00684.
    OMAi WSPDPRG.
    OrthoDBi EOG6WX4R3.

    Enzyme and pathway databases

    BioCyci PAER557722:GHJW-2524-MONOMER.

    Family and domain databases

    HAMAPi MF_00688. Leu_Phe_trans.
    InterProi IPR016181. Acyl_CoA_acyltransferase.
    IPR004616. Leu/Phe-tRNA_Trfase.
    [Graphical view ]
    Pfami PF03588. Leu_Phe_trans. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55729. SSF55729. 1 hit.
    TIGRFAMsi TIGR00667. aat. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool epidemic strain of Pseudomonas aeruginosa."
      Winstanley C., Langille M.G.I., Fothergill J.L., Kukavica-Ibrulj I., Paradis-Bleau C., Sanschagrin F., Thomson N.R., Winsor G.L., Quail M.A., Lennard N., Bignell A., Clarke L., Seeger K., Saunders D., Harris D., Parkhill J., Hancock R.E.W., Brinkman F.S.L., Levesque R.C.
      Genome Res. 19:12-23(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LESB58.

    Entry informationi

    Entry nameiLFTR_PSEA8
    AccessioniPrimary (citable) accession number: B7UV24
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3