B7URT2 (B7URT2_ECO27) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Predicted dethiobiotin synthetase, with altered C-ter by frameshift mutation EMBL CAS09225.1

Gene names

Name:	ynfK EMBL CAS09225.1
Ordered Locus Names:	E2348C_1677 EMBL CAS09225.1

Organism

Escherichia coli O127:H6 (strain E2348/69 / EPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

574521 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472
Catalytic activity	ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472
Cofactor	Magnesium By similarity. SAAS SAAS004472
Pathway	Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472
Subcellular location	Cytoplasm By similarity SAAS SAAS004472.

Ontologies

Keywords
Biological process	Biotin biosynthesis SAAS SAAS004472
Cellular component	Cytoplasm SAAS SAAS004472
Ligand	ATP-binding SAAS SAAS004472 Magnesium SAAS SAAS004472 Metal-binding SAAS SAAS004472 Nucleotide-binding
Molecular function	Ligase SAAS SAAS004472
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	biotin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW dethiobiotin synthase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7URT2 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: AC0812AD58DDDE64	FASTA	217	23,541
	10 20 30 40 50 60 MLKRFFITGT DTSVGKTVVS RALLQALASQ GKTVAGYKPV AKGSKETPEG LRNKDALVLQ 70 80 90 100 110 120 SVSTIELPYE AVNPIALSEE ESSVAHSCPI NYTLISNGLA NLTDKVDHVV VEGTGGWRSL 130 140 150 160 170 180 MNDLRPLSEW VVQEQLPVLM VVGIQEGCIN HALLTAQAIA NDGLPLMLAG WLTESIQDLR 190 200 210 IMRKSLMCSV KNFRHRSLVN CLICRAPNSV NWGNTSA

References

[1]

"Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69." Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G. J. Bacteriol. 191:347-354(2009) [PubMed: 18952797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: E2348/69 / EPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM180568 Genomic DNA. Translation: CAS09225.1.
RefSeq	YP_002329199.1. NC_011601.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7URT2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000115130; EBESCP00000107861; EBESCG00000114794.
GeneID	7062807.
GenomeReviews	Gene locus E2348_C_1677 in contig FM180568_GR.
KEGG	ecg:E2348C_1677.
PATRIC	18342375. VBIEscCol90278_1714.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000010427.
HOGENOM	HBG650065.
OMA	INPGLSH.
Family and domain databases
HAMAP	MF_00336. BioD. [Tree]
InterPro	IPR002586. CbiA_P_synth. IPR004472. DTB_synth_BioD. [Graphical view]
KO	K01935.
Pfam	PF01656. CbiA. 1 hit. [Graphical view]
PIRSF	PIRSF006755. DTB_synth. 1 hit.
TIGRFAMs	TIGR00347. BioD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7URT2_ECO27

Accession

Primary (citable) accession number: B7URT2

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)