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B7URP8

- UXAB_ECO27

UniProt

B7URP8 - UXAB_ECO27

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Protein

Altronate oxidoreductase

Gene
uxaB, E2348C_1642
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 2912NAD By similarityAdd
BLAST

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. tagaturonate reductase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciECOL574521:GJAO-1696-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductase (EC:1.1.1.58)
Alternative name(s):
Tagaturonate dehydrogenase
Tagaturonate reductase
Gene namesi
Name:uxaB
Ordered Locus Names:E2348C_1642
OrganismiEscherichia coli O127:H6 (strain E2348/69 / EPEC)
Taxonomic identifieri574521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000008205: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 483483Altronate oxidoreductaseUniRule annotationPRO_1000147657Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi574521.E2348C_1642.

Structurei

3D structure databases

ProteinModelPortaliB7URP8.
SMRiB7URP8. Positions 2-482.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0246.
KOiK00041.
OMAiHNTFCST.
OrthoDBiEOG6CVVB8.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPiMF_00670. Altron_oxidoreduct.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

B7URP8-1 [UniParc]FASTAAdd to Basket

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MKTLNRRDFP GAQYPERIIQ FGEGNFLRAF VDWQIDLLNE HTDLNSGVVV    50
VRPIETSFPP SLSTQDGLYT TIIRGLNEKG EAVSDARLIR SVNREISVYS 100
EYDEFLKLAH NPEMRFVFSN TTEAGISYHA GDKFDDAPAV SYPAKLTRLL 150
FERFSHFNGA LDKGWIIIPC ELIDYNGDAL RELVLRYAQE WALPEAFIQW 200
LDQANSFCST LVDRIVTGYP RDEVAKLEEE LGYHDGFLDT AEHFYLFVIQ 250
GPKSLATELR LDKYPLNVLI VDDIKPYKER KVAILNGAHT ALVPVAFQAG 300
LDTVGEAMND AEICAFVEKA IYEEIIPVLD LPRDELESFA SAVTGRFRNP 350
YIKHQLLSIA LNGMTKFRTR ILPQLLAGQK ANGTLPARLT FALAALIAFY 400
RGERNGETYP VQDDAHWLER YQQLWSQYRD RVIGTQELVA IVLAEKDHWE 450
QDLTQVPGLV EQVANDLDAI LEKGMREAVR PLC 483
Length:483
Mass (Da):54,834
Last modified:February 10, 2009 - v1
Checksum:i4EA4766DF35BC2FD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM180568 Genomic DNA. Translation: CAS09190.1.
RefSeqiYP_002329165.1. NC_011601.1.

Genome annotation databases

EnsemblBacteriaiCAS09190; CAS09190; E2348C_1642.
GeneIDi7062047.
KEGGiecg:E2348C_1642.
PATRICi18342301. VBIEscCol90278_1677.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM180568 Genomic DNA. Translation: CAS09190.1 .
RefSeqi YP_002329165.1. NC_011601.1.

3D structure databases

ProteinModelPortali B7URP8.
SMRi B7URP8. Positions 2-482.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 574521.E2348C_1642.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAS09190 ; CAS09190 ; E2348C_1642 .
GeneIDi 7062047.
KEGGi ecg:E2348C_1642.
PATRICi 18342301. VBIEscCol90278_1677.

Phylogenomic databases

eggNOGi COG0246.
KOi K00041.
OMAi HNTFCST.
OrthoDBi EOG6CVVB8.

Enzyme and pathway databases

UniPathwayi UPA00246 .
BioCyci ECOL574521:GJAO-1696-MONOMER.

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
HAMAPi MF_00670. Altron_oxidoreduct.
InterProi IPR008927. 6-PGluconate_DH_C-like.
IPR023668. Altronate_OxRdtase.
IPR013328. DH_multihelical.
IPR013118. Mannitol_DH_C.
IPR013131. Mannitol_DH_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF01232. Mannitol_dh. 1 hit.
PF08125. Mannitol_dh_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48179. SSF48179. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69."
    Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.
    J. Bacteriol. 191:347-354(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E2348/69 / EPEC.

Entry informationi

Entry nameiUXAB_ECO27
AccessioniPrimary (citable) accession number: B7URP8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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