B7UQZ8 (B7UQZ8_ECO27) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase C HAMAP MF_01862
EC=2.1.1.172 HAMAP MF_01862

Alternative name(s):
16S rRNA m2G1207 methyltransferase HAMAP MF_01862
rRNA (guanine-N(2)-)-methyltransferase RsmC HAMAP MF_01862

Gene names

Name:	rsmC HAMAP MF_01862 EMBL CAS12216.1
Ordered Locus Names:	E2348C_4668 EMBL CAS12216.1

Organism

Escherichia coli O127:H6 (strain E2348/69 / EPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

574521 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle By similarity. HAMAP MF_01862 SAAS SAAS013675
Catalytic activity	S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1207) in 16S rRNA. HAMAP MF_01862 SAAS SAAS013675
Subunit structure	Monomer By similarity. HAMAP MF_01862 SAAS SAAS013675
Subcellular location	Cytoplasm By similarity HAMAP MF_01862 SAAS SAAS013675.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmC family. HAMAP MF_01862

Ontologies

Keywords
Biological process	rRNA processing HAMAP MF_01862 SAAS SAAS013675
Cellular component	Cytoplasm HAMAP MF_01862 SAAS SAAS013675
Ligand	S-adenosyl-L-methionine HAMAP MF_01862 SAAS SAAS013675
Molecular function	Methyltransferase HAMAP MF_01862 SAAS SAAS013675 EMBL CAS12216.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7UQZ8 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 573CC1F13031F977	FASTA	343	37,653
	10 20 30 40 50 60 MSAFTPASEV LLRHSDDFEQ SRILFAGDLQ DDLPARLDTA VSRAHTQQFH HWQVLSRQMG 70 80 90 100 110 120 DNARFSLVAT ADDVADCDTL IYYWPKNKPE AQFQLMNLLS LLPVGTDIFV VGENRSGVRS 130 140 150 160 170 180 AEQMLADYAP LNKVDSARRC GLYFGRLEKQ PVFDAEKFWG EYSVDGLTVK TLPGVFSRDG 190 200 210 220 230 240 LDVGSQLLLS TLTPHTKGKV LDVGCGAGVL SVAFARHSPK IRLTLCDVSA PAVEASRATL 250 260 270 280 290 300 AANGVEGEVF ASNVFSEVKG RFDMIISNPP FHDGMQTSLD AAQTLIRGAV RHLNSGGELR 310 320 330 340 IVANAFLPYP DVLDETFGFH EVIAQTGRFK VYRAIMTRQA KKG

References

[1]

"Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69." Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G. J. Bacteriol. 191:347-354(2009) [PubMed: 18952797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: E2348/69 / EPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM180568 Genomic DNA. Translation: CAS12216.1.
RefSeq	YP_002332113.1. NC_011601.1.
3D structure databases
ProteinModelPortal	B7UQZ8.
ModBase	Search...
Protein-protein interaction databases
STRING	B7UQZ8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000111501; EBESCP00000106801; EBESCG00000110463.
GeneID	7061529.
GenomeReviews	Gene locus E2348_C_4668 in contig FM180568_GR.
KEGG	ecg:E2348C_4668.
PATRIC	18348654. VBIEscCol90278_4775.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000009812.
HOGENOM	HBG296757.
OMA	TGKFKVY.
ProtClustDB	PRK09489.
Family and domain databases
HAMAP	MF_01862. 16SrRNA_methyltr_C. [Tree]
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. IPR013675. Mtase_sm_N. IPR023543. rRNA_ssu_MeTfrase_C. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. PF08468. MTS_N. 1 hit. [Graphical view]
PROSITE	PS00092. N6_MTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7UQZ8_ECO27

Accession

Primary (citable) accession number: B7UQZ8

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)