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B7UJ61

- B7UJ61_ECO27

UniProt

B7UJ61 - B7UJ61_ECO27

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Protein

tRNA pseudouridine synthase B

Gene
truB, E2348C_3447
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity.UniRule annotationSAAS annotations

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431Substrate By similarityUniRule annotation
Active sitei48 – 481Nucleophile By similarityUniRule annotation
Binding sitei76 – 761Substrate By similarityUniRule annotation
Binding sitei179 – 1791Substrate By similarityUniRule annotation
Binding sitei200 – 2001Substrate By similarityUniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotations

Keywords - Biological processi

tRNA processingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciECOL574521:GJAO-3573-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene namesi
Name:truBUniRule annotationImported
Ordered Locus Names:E2348C_3447Imported
OrganismiEscherichia coli O127:H6 (strain E2348/69 / EPEC)Imported
Taxonomic identifieri574521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000008205: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi574521.E2348C_3447.

Structurei

3D structure databases

ProteinModelPortaliB7UJ61.
SMRiB7UJ61. Positions 10-311.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231223.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

B7UJ61-1 [UniParc]FASTAAdd to Basket

« Hide

MSRPRRRGRD INGVLLLDKP QGMSSNDALQ KVKRIYNANR AGHTGALDPL    50
ATGMLPICLG EATKFSQYLL DSDKRYRVIA RLGQRTDTSD ADGQIVEERP 100
VTFSAEQLAA ALDTFRGDIE QIPSMYSALK YQGKKLYEYA RQGIEVPREA 150
RPITVYELLF IRHEGNELEL EIHCSKGTYI RTIIDDLGEK LGCGAHVIYL 200
RRLAVSKYPV ERMVTLEHLR ELVEQAEQQD IPAAELLDPL LMPMDSPASD 250
YPVVNLPLTS SVYFKNGNPV RTSGAPLEGL VRVTEGENGK FIGMGEIDDE 300
GRVAPRRLVV EYPA 314
Length:314
Mass (Da):35,087
Last modified:February 10, 2009 - v1
Checksum:iFEA46C01E0E8E7A5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM180568 Genomic DNA. Translation: CAS10995.1.
RefSeqiYP_002330915.1. NC_011601.1.

Genome annotation databases

EnsemblBacteriaiCAS10995; CAS10995; E2348C_3447.
GeneIDi7061154.
KEGGiecg:E2348C_3447.
PATRICi18346058. VBIEscCol90278_3520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM180568 Genomic DNA. Translation: CAS10995.1 .
RefSeqi YP_002330915.1. NC_011601.1.

3D structure databases

ProteinModelPortali B7UJ61.
SMRi B7UJ61. Positions 10-311.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 574521.E2348C_3447.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAS10995 ; CAS10995 ; E2348C_3447 .
GeneIDi 7061154.
KEGGi ecg:E2348C_3447.
PATRICi 18346058. VBIEscCol90278_3520.

Phylogenomic databases

eggNOGi COG0130.
HOGENOMi HOG000231223.
KOi K03177.
OMAi YELQFIR.
OrthoDBi EOG6358D3.

Enzyme and pathway databases

BioCyci ECOL574521:GJAO-3573-MONOMER.

Family and domain databases

Gene3Di 2.30.130.10. 1 hit.
HAMAPi MF_01080. TruB_bact.
InterProi IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view ]
PANTHERi PTHR13767. PTHR13767. 1 hit.
Pfami PF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsi TIGR00431. TruB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69."
    Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.
    J. Bacteriol. 191:347-354(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E2348/69 / EPEC.

Entry informationi

Entry nameiB7UJ61_ECO27
AccessioniPrimary (citable) accession number: B7UJ61
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: June 11, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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