B7UJ45 (DIAA_ECO27) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DnaA initiator-associating protein DiaA

Gene names

Name:	diaA
Ordered Locus Names:	E2348C_3431

Organism

Escherichia coli O127:H6 (strain E2348/69 / EPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

574521 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O127:H6

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein By similarity. HAMAP-Rule MF_01157
Subunit structure	Homotetramer; dimer of dimers By similarity.
Sequence similarities	Belongs to the SIS family. DiaA subfamily. Contains 1 SIS domain.

Ontologies

Keywords
Biological process	DNA replication
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA replication Inferred from electronic annotation. Source: HAMAP carbohydrate metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	DnaA initiator-associating protein DiaA HAMAP-Rule MF_01157		PRO_1000164293
Regions
	Domain	34 – 196	163	SIS

Sequences

	Sequence		Length	Mass (Da)
	B7UJ45 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: E1CDFE9C0DF365A8	FASTA	196	21,090
	10 20 30 40 50 60 MQERIKACFT ESIQTQIAAA EALPDAISRA AMTLVQSLLN GNKILCCGNG TSAANAQHFA 70 80 90 100 110 120 ASMINRFETE RPSLPAIALN TDNVVLTAIA NDRLHDEVYA KQVRALGHAG DVLLAISTRG 130 140 150 160 170 180 NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGPQDVE IRIPSHRSAR IQEMHMLTVN 190 CLCDLIDNTL FPHQDV

References

[1]

"Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69." Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G. J. Bacteriol. 191:347-354(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: E2348/69 / EPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM180568 Genomic DNA. Translation: CAS10979.1.
RefSeq	YP_002330899.1. NC_011601.1.
3D structure databases
ProteinModelPortal	B7UJ45.
SMR	B7UJ45. Positions 1-193.
ModBase	Search...
Protein-protein interaction databases
STRING	574521.E2348C_3431.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAS10979; CAS10979; E2348C_3431.
GeneID	7063217.
KEGG	ecg:E2348C_3431.
PATRIC	18346024. VBIEscCol90278_3503.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0279.
KO	K12961.
OMA	CLCDGVD.
ProtClustDB	PRK10886.
Enzyme and pathway databases
BioCyc	ECOL574521:GJAO-3555-MONOMER.
Family and domain databases
HAMAP	MF_01157. SIS_DiaA.
InterPro	IPR023070. DiaA. IPR001347. SIS. [Graphical view]
Pfam	PF13580. SIS_2. 1 hit. [Graphical view]
PROSITE	PS51464. SIS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DIAA_ECO27

Accession

Primary (citable) accession number: B7UJ45

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	February 10, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program