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B7UJ18

- B7UJ18_ECO27

UniProt

B7UJ18 - B7UJ18_ECO27

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Protein
Submitted name:

Pyruvate formate-lyase 4/2-ketobutyrate formate-lyase

Gene

tdcE

Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei423 – 4231S-acetylcysteine intermediateUniRule annotation
Active sitei424 – 4241Cysteine radical intermediateUniRule annotation

GO - Molecular functioni

  1. formate C-acetyltransferase activity Source: InterPro
  2. lyase activity Source: UniProtKB-KW

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Keywords - Ligandi

PyruvateImported

Enzyme and pathway databases

BioCyciECOL574521:GJAO-3527-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate formate-lyase 4/2-ketobutyrate formate-lyaseImported
Gene namesi
Name:tdcEImported
Ordered Locus Names:E2348C_3404Imported
OrganismiEscherichia coli O127:H6 (strain E2348/69 / EPEC)Imported
Taxonomic identifieri574521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000008205: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei739 – 7391Glycine radicalUniRule annotation

Keywords - PTMi

Organic radicalUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi574521.E2348C_3404.

Family & Domainsi

Sequence similaritiesi

Contains glycine radical domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1882.
HOGENOMiHOG000011346.
KOiK00656.
OMAiFDAYGRE.
OrthoDBiEOG6Q8J0J.

Family and domain databases

InterProiIPR005949. Form_AcTrfase.
IPR019777. Form_AcTrfase_GR_CS.
IPR001150. Gly_radical.
IPR004184. PFL_dom.
[Graphical view]
PfamiPF01228. Gly_radical. 1 hit.
PF02901. PFL. 1 hit.
[Graphical view]
PIRSFiPIRSF000379. For_Ac_trans_1. 1 hit.
TIGRFAMsiTIGR01255. pyr_form_ly_1. 1 hit.
PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
PS51149. GLY_RADICAL_2. 1 hit.
PS51554. PFL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7UJ18-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVDIDTSDK LYADAWLGFK GTDWKNEINV RDFIQHNYTP YEGDESFLAE
60 70 80 90 100
ATPATTELWE KVMEGIRIEN ATHAPLDFDT NIATTITAHD AGYIDQPLEK
110 120 130 140 150
IVGLQTDAPL KRALHPFGGI NMIRSSFHAY GREMDSEFEY IFTDLRKTHN
160 170 180 190 200
QGVFDVYSPD MLRCRKSGVL TGLPDGYGRG RIIGDYRRVA LYGISYLVRE
210 220 230 240 250
RELQFADLQS RLEKGEDLEA TIRLREELAE HRRALLQIQE MAAKYGFDIS
260 270 280 290 300
RPAQNAQEAV QWIYFAYLAA VKSQNGGAMS LGRTASFLDI YIERDFKAGV
310 320 330 340 350
LNEQQAQELI DHFIMKIRMV RFLRTPEFDS LFSGDPIWAT EVIGGMGLDG
360 370 380 390 400
RTLVTKNSFR YLHTLHTMGP APEPNLTILW SEALPIAFKK YAAQVSIVTS
410 420 430 440 450
SLQYENDDLM RTDFNSDDYA IACCVSPMVI GKQMQFFGAR ANLAKTLLYA
460 470 480 490 500
INGGMDEKLK IQVGPKTAPL MDDVLDYDKV MDSLDHFMDW LAVQYISALN
510 520 530 540 550
IIHYMHDKYS YEASLMALHD RDVYRTMACG IAGLSVATDS LSAIKYARVK
560 570 580 590 600
PIRDENGLAV DFEIDGEYPQ YGNNDERVDS IACDLVERFM KKIKALPTYR
610 620 630 640 650
NAVPTQSILT ITSNVVYGQK TGNTPDGRRA GTPFAPGANP MHGRDRKGAV
660 670 680 690 700
ASLTSVAKLP FTYAKDGISY TFSIVPAALG KEDPIRKTNL VGLLDGYFHH
710 720 730 740 750
EADVEGGQHL NVNVMNREML LDAIEHPEKY PNLTIRVSGY AVRFNALTRE
760
QQQDVISRTF TQAL
Length:764
Mass (Da):85,986
Last modified:February 10, 2009 - v1
Checksum:i34BA82D5865CBFB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM180568 Genomic DNA. Translation: CAS10952.1.
RefSeqiYP_002330872.1. NC_011601.1.

Genome annotation databases

EnsemblBacteriaiCAS10952; CAS10952; E2348C_3404.
GeneIDi7061770.
KEGGiecg:E2348C_3404.
PATRICi18345968. VBIEscCol90278_3475.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM180568 Genomic DNA. Translation: CAS10952.1 .
RefSeqi YP_002330872.1. NC_011601.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 574521.E2348C_3404.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAS10952 ; CAS10952 ; E2348C_3404 .
GeneIDi 7061770.
KEGGi ecg:E2348C_3404.
PATRICi 18345968. VBIEscCol90278_3475.

Phylogenomic databases

eggNOGi COG1882.
HOGENOMi HOG000011346.
KOi K00656.
OMAi FDAYGRE.
OrthoDBi EOG6Q8J0J.

Enzyme and pathway databases

BioCyci ECOL574521:GJAO-3527-MONOMER.

Family and domain databases

InterProi IPR005949. Form_AcTrfase.
IPR019777. Form_AcTrfase_GR_CS.
IPR001150. Gly_radical.
IPR004184. PFL_dom.
[Graphical view ]
Pfami PF01228. Gly_radical. 1 hit.
PF02901. PFL. 1 hit.
[Graphical view ]
PIRSFi PIRSF000379. For_Ac_trans_1. 1 hit.
TIGRFAMsi TIGR01255. pyr_form_ly_1. 1 hit.
PROSITEi PS00850. GLY_RADICAL_1. 1 hit.
PS51149. GLY_RADICAL_2. 1 hit.
PS51554. PFL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69."
    Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.
    J. Bacteriol. 191:347-354(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: E2348/69 / EPECImported.

Entry informationi

Entry nameiB7UJ18_ECO27
AccessioniPrimary (citable) accession number: B7UJ18
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: November 26, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3