Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B7UJ18

- B7UJ18_ECO27

UniProt

B7UJ18 - B7UJ18_ECO27

Protein
Submitted name:

Pyruvate formate-lyase 4/2-ketobutyrate formate-lyase

Gene

tdcE

Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei423 – 4231S-acetylcysteine intermediateUniRule annotation
    Active sitei424 – 4241Cysteine radical intermediateUniRule annotation

    GO - Molecular functioni

    1. formate C-acetyltransferase activity Source: InterPro
    2. lyase activity Source: UniProtKB-KW

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    LyaseImported

    Keywords - Ligandi

    PyruvateImported

    Enzyme and pathway databases

    BioCyciECOL574521:GJAO-3527-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Pyruvate formate-lyase 4/2-ketobutyrate formate-lyaseImported
    Gene namesi
    Name:tdcEImported
    Ordered Locus Names:E2348C_3404Imported
    OrganismiEscherichia coli O127:H6 (strain E2348/69 / EPEC)Imported
    Taxonomic identifieri574521 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000008205: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei739 – 7391Glycine radicalUniRule annotation

    Keywords - PTMi

    Organic radicalUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi574521.E2348C_3404.

    Family & Domainsi

    Sequence similaritiesi

    Contains glycine radical domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1882.
    HOGENOMiHOG000011346.
    KOiK00656.
    OMAiFDAYGRE.
    OrthoDBiEOG6Q8J0J.

    Family and domain databases

    InterProiIPR005949. Form_AcTrfase.
    IPR019777. Form_AcTrfase_GR_CS.
    IPR001150. Gly_radical.
    IPR004184. PFL_dom.
    [Graphical view]
    PfamiPF01228. Gly_radical. 1 hit.
    PF02901. PFL. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000379. For_Ac_trans_1. 1 hit.
    TIGRFAMsiTIGR01255. pyr_form_ly_1. 1 hit.
    PROSITEiPS00850. GLY_RADICAL_1. 1 hit.
    PS51149. GLY_RADICAL_2. 1 hit.
    PS51554. PFL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7UJ18-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKVDIDTSDK LYADAWLGFK GTDWKNEINV RDFIQHNYTP YEGDESFLAE    50
    ATPATTELWE KVMEGIRIEN ATHAPLDFDT NIATTITAHD AGYIDQPLEK 100
    IVGLQTDAPL KRALHPFGGI NMIRSSFHAY GREMDSEFEY IFTDLRKTHN 150
    QGVFDVYSPD MLRCRKSGVL TGLPDGYGRG RIIGDYRRVA LYGISYLVRE 200
    RELQFADLQS RLEKGEDLEA TIRLREELAE HRRALLQIQE MAAKYGFDIS 250
    RPAQNAQEAV QWIYFAYLAA VKSQNGGAMS LGRTASFLDI YIERDFKAGV 300
    LNEQQAQELI DHFIMKIRMV RFLRTPEFDS LFSGDPIWAT EVIGGMGLDG 350
    RTLVTKNSFR YLHTLHTMGP APEPNLTILW SEALPIAFKK YAAQVSIVTS 400
    SLQYENDDLM RTDFNSDDYA IACCVSPMVI GKQMQFFGAR ANLAKTLLYA 450
    INGGMDEKLK IQVGPKTAPL MDDVLDYDKV MDSLDHFMDW LAVQYISALN 500
    IIHYMHDKYS YEASLMALHD RDVYRTMACG IAGLSVATDS LSAIKYARVK 550
    PIRDENGLAV DFEIDGEYPQ YGNNDERVDS IACDLVERFM KKIKALPTYR 600
    NAVPTQSILT ITSNVVYGQK TGNTPDGRRA GTPFAPGANP MHGRDRKGAV 650
    ASLTSVAKLP FTYAKDGISY TFSIVPAALG KEDPIRKTNL VGLLDGYFHH 700
    EADVEGGQHL NVNVMNREML LDAIEHPEKY PNLTIRVSGY AVRFNALTRE 750
    QQQDVISRTF TQAL 764
    Length:764
    Mass (Da):85,986
    Last modified:February 10, 2009 - v1
    Checksum:i34BA82D5865CBFB6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM180568 Genomic DNA. Translation: CAS10952.1.
    RefSeqiYP_002330872.1. NC_011601.1.

    Genome annotation databases

    EnsemblBacteriaiCAS10952; CAS10952; E2348C_3404.
    GeneIDi7061770.
    KEGGiecg:E2348C_3404.
    PATRICi18345968. VBIEscCol90278_3475.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FM180568 Genomic DNA. Translation: CAS10952.1 .
    RefSeqi YP_002330872.1. NC_011601.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 574521.E2348C_3404.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAS10952 ; CAS10952 ; E2348C_3404 .
    GeneIDi 7061770.
    KEGGi ecg:E2348C_3404.
    PATRICi 18345968. VBIEscCol90278_3475.

    Phylogenomic databases

    eggNOGi COG1882.
    HOGENOMi HOG000011346.
    KOi K00656.
    OMAi FDAYGRE.
    OrthoDBi EOG6Q8J0J.

    Enzyme and pathway databases

    BioCyci ECOL574521:GJAO-3527-MONOMER.

    Family and domain databases

    InterProi IPR005949. Form_AcTrfase.
    IPR019777. Form_AcTrfase_GR_CS.
    IPR001150. Gly_radical.
    IPR004184. PFL_dom.
    [Graphical view ]
    Pfami PF01228. Gly_radical. 1 hit.
    PF02901. PFL. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000379. For_Ac_trans_1. 1 hit.
    TIGRFAMsi TIGR01255. pyr_form_ly_1. 1 hit.
    PROSITEi PS00850. GLY_RADICAL_1. 1 hit.
    PS51149. GLY_RADICAL_2. 1 hit.
    PS51554. PFL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69."
      Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.
      J. Bacteriol. 191:347-354(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: E2348/69 / EPECImported.

    Entry informationi

    Entry nameiB7UJ18_ECO27
    AccessioniPrimary (citable) accession number: B7UJ18
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 10, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3