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Protein
Submitted name:

Fused aspartokinase I/homoserine dehydrogenase I

Gene

thrA

Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Fused aspartokinase I/homoserine dehydrogenase IImported
Gene namesi
Name:thrAImported
Ordered Locus Names:E2348C_0002Imported
OrganismiEscherichia coli O127:H6 (strain E2348/69 / EPEC)Imported
Taxonomic identifieri574521 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000008205 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliB7UI47.
SMRiB7UI47.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini320 – 394ACTInterPro annotationAdd BLAST75
Domaini401 – 478ACTInterPro annotationAdd BLAST78

Phylogenomic databases

HOGENOMiHOG000271593.
KOiK12524.
OMAiCNKIACS.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
InterProiView protein in InterPro
IPR036393. AceGlu_kinase-like_sf.
IPR002912. ACT_dom.
IPR001048. Asp/Glu/Uridylate_kinase.
IPR005106. Asp/hSer_DH_NAD-bd.
IPR001341. Asp_kinase.
IPR018042. Aspartate_kinase_CS.
IPR011147. Bifunc_aspartokin/hSer_DH.
IPR027795. GATS-like_ACT_dom.
IPR001342. HDH_cat.
IPR019811. HDH_CS.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF00696. AA_kinase. 1 hit.
PF01842. ACT. 1 hit.
PF13840. ACT_7. 1 hit.
PF00742. Homoserine_dh. 1 hit.
PF03447. NAD_binding_3. 1 hit.
PIRSFiPIRSF000727. ThrA. 1 hit.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00657. asp_kinases. 1 hit.
PROSITEiView protein in PROSITE
PS51671. ACT. 2 hits.
PS00324. ASPARTOKINASE. 1 hit.
PS01042. HOMOSER_DHGENASE. 1 hit.

Sequencei

Sequence statusi: Complete.

B7UI47-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLKFGGTS VANAERFLRV ADILESNARQ GQVATVLSAP AKITNHLVAM
60 70 80 90 100
IEKTISGQDA LPNISDAERI FAELLTGLAA AQPGFPLAQL KTFVDQEFAQ
110 120 130 140 150
IKHVLHGISL LGQCPDSINA ALICRGEKMS IAIMAGVLEA RGHNVTVIDP
160 170 180 190 200
VEKLLAVGHY LESTVDIAES TRRIAASRIP ADHMVLMAGF TAGNEKGELV
210 220 230 240 250
VLGRNGSDYS AAVLAACLRA DCCEIWTDVD GVYTCDPRQV PDARLLKSMS
260 270 280 290 300
YQEAMELSYF GAKVLHPRTI TPIAQFQIPC LIKNTGNPQA PGTLIGASRD
310 320 330 340 350
EDELPVKGIS NLNNMAMFSV SGPGMKGMVG MAARVFAAMS RARISVVLIT
360 370 380 390 400
QSSSEYSISF CVPQSDCVRA ERAMQEEFYL ELKEGLLEPL AVTERLAIIS
410 420 430 440 450
VVGDGMRTLR GISAKFFAAL ARANINIVAI AQGSSERSIS VVVNNDDATT
460 470 480 490 500
GVRVTHQMLF NTDQVIEVFV IGVGGVGGAL LEQLKRQQSW LKNKHIDLRV
510 520 530 540 550
CGVANSKALL TNVHGLNLEN WQEELAQAKE PFNLGRLIRL VKEYHLLNPV
560 570 580 590 600
IVDCTSSQAV ADQYADFLRE GFHVVTPNKK ANTSSMDYYH QLRYAAEKSR
610 620 630 640 650
RKFLYDTNVG AGLPVIENLQ NLLNAGDELM KFSGILSGSL SYIFGKLDEG
660 670 680 690 700
MSFSEATTLA REMGYTEPDP RDDLSGMDVA RKLLILARET GRELELADIE
710 720 730 740 750
IEPVLPAEFN AEGDVAAFMA NLSQLDDLFA ARVAKARDEG KVLRYVGNID
760 770 780 790 800
EDGVCRVKIA EVDGNDPLFK VKNGENALAF YSHYYQPLPL VLRGYGAGND
810 820
VTAAGVFADL LRTLSWKLGV
Length:820
Mass (Da):89,120
Last modified:February 10, 2009 - v1
Checksum:i0BF28E9EECAB10ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM180568 Genomic DNA. Translation: CAS07550.1.
RefSeqiWP_001264707.1. NC_011601.1.

Genome annotation databases

EnsemblBacteriaiCAS07550; CAS07550; E2348C_0002.
KEGGiecg:E2348C_0002.

Similar proteinsi

Entry informationi

Entry nameiB7UI47_ECO27
AccessioniPrimary (citable) accession number: B7UI47
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported