ID B7SNI6_ACORU Unreviewed; 76 AA. AC B7SNI6; DT 10-FEB-2009, integrated into UniProtKB/TrEMBL. DT 10-FEB-2009, sequence version 1. DT 27-MAR-2024, entry version 35. DE RecName: Full=Cocaine- and amphetamine-regulated transcript protein {ECO:0000256|ARBA:ARBA00018493}; DE Flags: Fragment; OS Acomys russatus (Golden spiny mouse) (Acomys lewisi). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Deomyinae; Acomys. OX NCBI_TaxID=60746 {ECO:0000313|EMBL:ACD80344.1}; RN [1] {ECO:0000313|EMBL:ACD80344.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=18843093; DOI=10.1152/ajpregu.00105.2008; RA Gutman R., Hacmon-Keren R., Choshniak I., Kronfeld-Schor N.; RT "Effect of food availability and leptin on the physiology and hypothalamic RT gene expression of the golden spiny mouse: a desert rodent that does not RT hoard food."; RL Am. J. Physiol. Regul. Integr. Comp. Physiol. 295:R2015-R2023(2008). CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}. CC -!- SIMILARITY: Belongs to the CART family. CC {ECO:0000256|ARBA:ARBA00005294}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; EU477391; ACD80344.1; -; mRNA. DR AlphaFoldDB; B7SNI6; -. DR GO; GO:0005615; C:extracellular space; IEA:InterPro. DR GO; GO:0045202; C:synapse; IEA:GOC. DR GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro. DR GO; GO:0008343; P:adult feeding behavior; IEA:InterPro. DR GO; GO:0009267; P:cellular response to starvation; IEA:InterPro. DR GO; GO:0007268; P:chemical synaptic transmission; IEA:UniProtKB-KW. DR GO; GO:0032099; P:negative regulation of appetite; IEA:InterPro. DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW. DR GO; GO:0043410; P:positive regulation of MAPK cascade; IEA:InterPro. DR CDD; cd22741; CART_CTD-like; 1. DR Gene3D; 4.10.40.30; CART, C-terminal domain; 1. DR InterPro; IPR009106; CART. DR InterPro; IPR036722; CART_C_sf. DR PANTHER; PTHR16655; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN; 1. DR PANTHER; PTHR16655:SF0; COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT PROTEIN; 1. DR Pfam; PF06373; CART; 1. DR SUPFAM; SSF64546; Satiety factor CART (cocaine and amphetamine regulated transcript); 1. PE 2: Evidence at transcript level; KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685}; KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157}; KW Neuropeptide {ECO:0000256|ARBA:ARBA00023320}; KW Neurotransmitter {ECO:0000256|ARBA:ARBA00022894}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}. FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:ACD80344.1" SQ SEQUENCE 76 AA; 8476 MW; F3207ED3859E5CA8 CRC64; YSAVDDASHE KELIEALQEV LKKLKSKRIP IYEKKYGQVP MCDAGEQCAV RKGARIGKLC DCPRGTSCNS FLLKCL //