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Protein
Submitted name:

STAT4

Gene

STAT4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: Ensembl
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. signal transducer activity Source: InterPro

GO - Biological processi

  1. cell proliferation Source: Ensembl
  2. cytokine-mediated signaling pathway Source: Ensembl
  3. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  4. protein phosphorylation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
STAT4Imported
Gene namesi
Name:STAT4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiB7SIX5.
ExpressionAtlasiB7SIX5. baseline and differential.

Family & Domainsi

Family and domain databases

Gene3Di1.10.532.10. 1 hit.
InterProiIPR001217. STAT.
IPR029839. STAT4.
IPR013799. STAT_TF_prot_interaction.
[Graphical view]
PANTHERiPTHR11801. PTHR11801. 1 hit.
PTHR11801:SF19. PTHR11801:SF19. 1 hit.
PfamiPF02865. STAT_int. 1 hit.
[Graphical view]
SUPFAMiSSF48092. SSF48092. 1 hit.

Sequencei

Sequence statusi: Fragment.

B7SIX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQWNQVQQL EIKFLEQVDQ FYDDNFPMEI RHLLAQWIEN QDWEAASNNE

TM
Length:52
Mass (Da):6,403
Last modified:February 9, 2009 - v1
Checksum:i9C4EDC8322787BE4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei52 – 521Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU304790 mRNA. Translation: ACA01859.1.
EU304791 mRNA. Translation: ACA01860.1.
UniGeneiHs.735572.
Hs.80642.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU304790 mRNA. Translation: ACA01859.1.
EU304791 mRNA. Translation: ACA01860.1.
UniGeneiHs.735572.
Hs.80642.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35478581.

Gene expression databases

BgeeiB7SIX5.
ExpressionAtlasiB7SIX5. baseline and differential.

Family and domain databases

Gene3Di1.10.532.10. 1 hit.
InterProiIPR001217. STAT.
IPR029839. STAT4.
IPR013799. STAT_TF_prot_interaction.
[Graphical view]
PANTHERiPTHR11801. PTHR11801. 1 hit.
PTHR11801:SF19. PTHR11801:SF19. 1 hit.
PfamiPF02865. STAT_int. 1 hit.
[Graphical view]
SUPFAMiSSF48092. SSF48092. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Association of STAT4 with human lupus."
    Kozyrev S.V., Abelson A.-K., Alarcon-Riquelme M.E.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: SpleenImported.

Entry informationi

Entry nameiB7SIX5_HUMAN
AccessioniPrimary (citable) accession number: B7SIX5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2009
Last sequence update: February 9, 2009
Last modified: January 6, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.