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Protein

Glycerol-3-phosphate dehydrogenase

Gene

IscW_ISCW023707

Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Keywords - Ligandi

CalciumUniRule annotation, FlavoproteinUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenaseUniRule annotation (EC:1.1.5.3UniRule annotation)
Gene namesi
ORF Names:IscW_ISCW023707Imported
OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
Taxonomic identifieri6945 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes
ProteomesiUP000001555: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi6945.ISCW023707-PA.

Structurei

3D structure databases

ProteinModelPortaliB7QKE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0578.
InParanoidiB7QKE4.
KOiK00111.
OMAiKHLTESY.
OrthoDBiEOG74TWZ2.
PhylomeDBiB7QKE4.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF13405. EF-hand_6. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7QKE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTLRSQLG TPDPLQRVEP SSSLRISRIH RADHTCRFHP EPRSSRPPRN
60 70 80 90 100
TEFDVLVIGG GATGAGVALD SVTRGFKTAM VEIYDFSAGT SSRSTKLIHG
110 120 130 140 150
GVRYLQKAIM NLDIEQYRMV REALQERANL LTIAPHLSTP LPIMLPIYRW
160 170 180 190 200
WQVPYYWVGI KMYDLVAGKQ CLKKSYFLSS KRCLELFPML KKEHLCGGLV
210 220 230 240 250
YYDGQHNDAR MNISIALTAA RNGASIANHT AVIGLLKKRD KDGKEVVSGA
260 270 280 290 300
RVKDMLTGDE FEVKAKCVVN ATGPFTDTIR KMDDPNAKPI CQPSSGVHIV
310 320 330 340 350
LPDYYSPDHM GLLDPDTSDG RVIFFLPWEN TTIAGTTDRP CPVTHYPAPT
360 370 380 390 400
EDDILFILNE VRHYLNQDVV VRRGDVLSAW AGIRPLVVDL NKTKPGKTEA
410 420 430 440 450
IARNHIIYIS DSNLVTIAGG KWTTYRVMAE HTMDAAVKAC GLEQQQRSTT
460 470 480 490 500
LGMTLEGGHT WTPTLYIRLV QDFGLEPDVA KHLSRSYGDR AVSVAKLAAL
510 520 530 540 550
TGKRWPVLGR RLHEEFPYIE AEVRYAIREY ACTAIDVIGR RMRLSFLNVQ
560 570 580 590 600
AAHECLPRVV DIMAEELQWS KARKDEELAK TREFLDVEMG GNVNKESQQK
610 620 630 640 650
LSMSFTKSEV DQYIQKFQAI DKDRKGYISV VDLRRSLKAA GESVSELQLH
660 670 680 690 700
EMLNEVDLNK NGQIELSEYL ELMNSLKTGS IAGSRLAKAV DLEYSRTLTV

DRSGGGL
Length:707
Mass (Da):79,143
Last modified:February 10, 2009 - v1
Checksum:iE865C4A6EFE646D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS959134 Genomic DNA. Translation: EEC19316.1.
RefSeqiXP_002415649.1. XM_002415604.1.
UniGeneiIsc.1033.

Genome annotation databases

EnsemblMetazoaiISCW023707-RA; ISCW023707-PA; ISCW023707.
GeneIDi8042570.
KEGGiisc:IscW_ISCW023707.
VectorBaseiISCW023707. Ixodes scapularis.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS959134 Genomic DNA. Translation: EEC19316.1.
RefSeqiXP_002415649.1. XM_002415604.1.
UniGeneiIsc.1033.

3D structure databases

ProteinModelPortaliB7QKE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6945.ISCW023707-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiISCW023707-RA; ISCW023707-PA; ISCW023707.
GeneIDi8042570.
KEGGiisc:IscW_ISCW023707.
VectorBaseiISCW023707. Ixodes scapularis.

Organism-specific databases

CTDi8042570.

Phylogenomic databases

eggNOGiCOG0578.
InParanoidiB7QKE4.
KOiK00111.
OMAiKHLTESY.
OrthoDBiEOG74TWZ2.
PhylomeDBiB7QKE4.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
PF13405. EF-hand_6. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
SMARTiSM00054. EFh. 2 hits.
[Graphical view]
PROSITEiPS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 2 hits.
PS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WikelImported.

Entry informationi

Entry nameiB7QKE4_IXOSC
AccessioniPrimary (citable) accession number: B7QKE4
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 7, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.