ID   B7QID8_IXOSC            Unreviewed;       238 AA.
AC   B7QID8;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   24-JAN-2024, entry version 76.
DE   SubName: Full=Glutamate decarboxylase, putative {ECO:0000313|EMBL:EEC18610.1, ECO:0000313|EnsemblMetazoa:ISCW014530-PA};
DE            EC=4.1.1.29 {ECO:0000313|EMBL:EEC18610.1};
GN   ORFNames=IscW_ISCW014530 {ECO:0000313|EMBL:EEC18610.1};
OS   Ixodes scapularis (Black-legged tick) (Deer tick).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX   NCBI_TaxID=6945;
RN   [1] {ECO:0000313|EMBL:EEC18610.1, ECO:0000313|Proteomes:UP000001555}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC   {ECO:0000313|EMBL:EEC18610.1};
RG   Ixodes scapularis Genome Project Consortium;
RA   Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA   Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA   Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA   Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT   "Annotation of Ixodes scapularis.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ISCW014530-PA}
RP   IDENTIFICATION.
RC   STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW014530-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|ARBA:ARBA00009533, ECO:0000256|RuleBase:RU000382}.
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DR   EMBL; ABJB010287120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010463666; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010536771; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010623785; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010771577; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB010855474; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB011046932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB011060142; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABJB011064576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DS945737; EEC18610.1; -; Genomic_DNA.
DR   RefSeq; XP_002414945.1; XM_002414900.1.
DR   AlphaFoldDB; B7QID8; -.
DR   STRING; 6945.B7QID8; -.
DR   PaxDb; 6945-B7QID8; -.
DR   EnsemblMetazoa; ISCW014530-RA; ISCW014530-PA; ISCW014530.
DR   KEGG; isc:IscW_ISCW014530; -.
DR   VEuPathDB; VectorBase:ISCI014530; -.
DR   VEuPathDB; VectorBase:ISCP_033425; -.
DR   VEuPathDB; VectorBase:ISCW014530; -.
DR   HOGENOM; CLU_1166993_0_0_1; -.
DR   InParanoid; B7QID8; -.
DR   Proteomes; UP000001555; Unassembled WGS sequence.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0004782; F:sulfinoalanine decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.170; -; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 2.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR021115; Pyridoxal-P_BS.
DR   PANTHER; PTHR45677:SF10; GLUTAMATE DECARBOXYLASE; 1.
DR   PANTHER; PTHR45677; GLUTAMATE DECARBOXYLASE-RELATED; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00392; DDC_GAD_HDC_YDC; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001555}.
SQ   SEQUENCE   238 AA;  27030 MW;  CF018BD6C1EB64EB CRC64;
     MNDVPTVRAG GSVSNLYAVM AARHKKFPDY KTLGLKALPQ LVMYTSEDSH YSVKGAGAAI
     GLGTDNVVSI PVDSRSDSVT WNPHKLMGTH LQCSTIHLKE DGLLLSCNQM CAEYLFQQDK
     HYDVSYDTGD KVPQCGRHND IFKLWLMWRA KPELVNVCFW YIPERLRNTP HSKQKEQQLG
     VVTAQLKARM MNTGTLMITY QPIWDKPNFF RNIVSNAGVR PEDIDFLVQE MDRLGHDL
//