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Protein

Elongation factor Tu

Gene

IscW_ISCW010766

Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-KW
  3. nucleotidyltransferase activity Source: UniProtKB-KW
  4. translation elongation factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported, NucleotidyltransferaseImported, Transferase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Gene namesi
ORF Names:IscW_ISCW010766Imported
OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
Taxonomic identifieri6945 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes
ProteomesiUP000001555: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi6945.ISCW010766-PA.

Structurei

3D structure databases

ProteinModelPortaliB7Q505.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
InParanoidiB7Q505.
KOiK02358.
OMAiYRKYDEI.
OrthoDBiEOG73BVCN.
PhylomeDBiB7Q505.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Q505-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSTLLGRFL CSGSGPLKAV ASKPLVAVPS AAAAACRLWV VLPRRCLATP
60 70 80 90 100
SPAAKKVYQR EKPHCNIGTI GHVDHGKTTL TAAITKVLAE EKLAAAKKYE
110 120 130 140 150
EIDNAPEEQA RGITINVAHV EYSTANRHYG HTDCPGHADY IKNMITGTSQ
160 170 180 190 200
MDGAILVVAA TDGAMPQTRE HLLLAKQIGI EHIVVYLNKA DAADKEMLEL
210 220 230 240 250
VEIELRELLT EHGYKGDEVP IVTGSALCAL EGREPDLGKD SILKLLDTVD
260 270 280 290 300
SHIPTPQRDL DKPFLMPIES VYSIPGRGTV VTGRLDRGIV KKGMECEIVG
310 320 330 340 350
YNKFFKTTVT GIEMFHKILE EAQAGDQLGA LIRGIKRDEV RRGMVLCKPG
360 370 380 390 400
TIKQHDQYEA QVYVLKKEEG GRERPILKRY QPIVFSTTWD CPARITVEGR
410 420 430 440 450
DMVMPGEDCK LIVKLFKPMA LEQGQRFTLR DGSRTSGTGV VTKVLNNLTP
460 470
DERADLEKSE KKKEKEALKR AQKGA
Length:475
Mass (Da):52,235
Last modified:February 10, 2009 - v1
Checksum:i69C999FC1D1002E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS858703 Genomic DNA. Translation: EEC13927.1.
RefSeqiXP_002401272.1. XM_002401228.1.
UniGeneiIsc.5677.

Genome annotation databases

EnsemblMetazoaiISCW010766-RA; ISCW010766-PA; ISCW010766.
GeneIDi8035998.
KEGGiisc:IscW_ISCW010766.
VectorBaseiISCW010766. Ixodes scapularis.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS858703 Genomic DNA. Translation: EEC13927.1.
RefSeqiXP_002401272.1. XM_002401228.1.
UniGeneiIsc.5677.

3D structure databases

ProteinModelPortaliB7Q505.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6945.ISCW010766-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiISCW010766-RA; ISCW010766-PA; ISCW010766.
GeneIDi8035998.
KEGGiisc:IscW_ISCW010766.
VectorBaseiISCW010766. Ixodes scapularis.

Organism-specific databases

CTDi8035998.

Phylogenomic databases

eggNOGiCOG0050.
InParanoidiB7Q505.
KOiK02358.
OMAiYRKYDEI.
OrthoDBiEOG73BVCN.
PhylomeDBiB7Q505.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WikelImported.

Entry informationi

Entry nameiB7Q505_IXOSC
AccessioniPrimary (citable) accession number: B7Q505
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 7, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.