B7PXW4 (B7PXW4_IXOSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroorotate dehydrogenase, putative EMBL EEC11436.1
EC=1.3.3.1 EMBL EEC11436.1

Gene names

ORF Names:

IscW_ISCW020699 EMBL EEC11436.1

Organism

Ixodes scapularis (Black-legged tick) (Deer tick)

Taxonomic identifier

6945 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Chelicerata › Arachnida › Acari › Parasitiformes › Ixodida › Ixodoidea › Ixodidae › Ixodinae › Ixodes

Protein attributes

Sequence length	375 AA.
Sequence status	Fragment.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL EEC11436.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	'de novo' pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro UMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	dihydroorotate oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	211	1	Nucleophile By similarity PIRSR PIRSR000164-1
Experimental info
	Non-terminal residue	1	1	EMBL EEC11436.1

Sequences

	Sequence		Length	Mass (Da)
	B7PXW4 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: A00C4A902541F50A	FASTA	375	40,304
	10 20 30 40 50 60 RGRVTPLCFQ YKLKSMAAVV GGAAVGFLGV AAASGNPDFY RDVAMPFVHR IMSPESAHRM 70 80 90 100 110 120 AILAARWQLV RGQRKPDPPV LCTELFGLSF ENPVGLAAGF DKHGEGVGGL ERWGFGFVEV 130 140 150 160 170 180 GSVTPLPQPG NPKPRVFRLA EDLAVINRYG FNSVGHDQVL SSLEAGRHGW KRPVGVNLGK 190 200 210 220 230 240 NKESASAADD YAQGVLKFGE LADYLVINVS SPNTPGLRGL QGQRELRQLL KQVLGARDSL 250 260 270 280 290 300 SKRTPVLVKV APDLSDQEKA DIAAVVTSKE CRVDGLVVCN TTVERPPELH SEHRHQAGGL 310 320 330 340 350 360 SGRPLTDLST RTIADMYRLT KGCMPIIGVG GVLTGEDAYA KVKAGASLLQ MYSALVFYGP 370 PAVCTVKERL AELLR

References

[1]

"Annotation of Ixodes scapularis." Ixodes scapularis Genome Project Consortium Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A. , Birren B., Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Wikel.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS816394 Genomic DNA. Translation: EEC11436.1.
RefSeq	XP_002401966.1. XM_002401922.1.
UniGene	Isc.20426.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7PXW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	ISCW020699-RA; ISCW020699-PA; ISCW020699.
GeneID	8032968.
KEGG	isc:IscW_ISCW020699.
VectorBase	ISCW020699. Ixodes scapularis.
Organism-specific databases
CTD	8032968.
Phylogenomic databases
GeneTree	EMGT00050000010553.
OMA	AALNRMG.
OrthoDB	EOG43BK4M.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR012135. Dihydroorotate_DH_1_2. IPR005719. Dihydroorotate_DH_2. IPR001295. Dihydroorotate_DH_CS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00254.
Pfam	PF01180. DHO_dh. 1 hit. [Graphical view]
PIRSF	PIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMs	TIGR01036. PyrD_sub2. 1 hit.
PROSITE	PS00911. DHODEHASE_1. 1 hit. PS00912. DHODEHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7PXW4_IXOSC

Accession

Primary (citable) accession number: B7PXW4

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	November 16, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)