B7PXS9 (B7PXS9_IXOSC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uroporphyrinogen decarboxylase RuleBase RU000554
EC=4.1.1.37 RuleBase RU000554

Gene names

ORF Names:

IscW_ISCW020804 EMBL EEC11401.1

Organism

Ixodes scapularis (Black-legged tick) (Deer tick)

Taxonomic identifier

6945 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Chelicerata › Arachnida › Acari › Parasitiformes › Ixodida › Ixodoidea › Ixodidae › Ixodinae › Ixodes

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Uroporphyrinogen III = coproporphyrinogen + 4 CO2. RuleBase RU000554
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen III from 5-aminolevulinate: step 4/4. RuleBase RU000554
Sequence similarities	Belongs to the uroporphyrinogen decarboxylase family. RuleBase RU004169

Ontologies

Keywords
Biological process	Porphyrin biosynthesis RuleBase RU000554
Molecular function	Decarboxylase RuleBase RU000554 Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	uroporphyrinogen decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7PXS9 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: DECE4565FC85E8D7	FASTA	346	39,906
	10 20 30 40 50 60 MKQILNPLKG NSNKIPIWFM RQAGRYLSEY KKVRETTKNF LDFCYDVNKA TEVTLQPIKR 70 80 90 100 110 120 YGFDAAIIFS DILVLPHALG WEVDFKENVG PILKQFKSQE DFKYLQSNPN NKLEKIYEII 130 140 150 160 170 180 KKVKKELPST TSLIGFAGSP WTVMSYMLEG KGKQDFKTSK KFIYENKILA KELLNFITEK 190 200 210 220 230 240 TADHLINQAR SGADVLKLFD SWSGVLAEEE FTEFVIEPTK KIILKVKEVF PKTPVIAFPK 250 260 270 280 290 300 GAGLLYEKFI KEVPIDILAV DQMIPLEKMK EWSDKVIVQG NLDPVVLLTN KEIIKEKAYK 310 320 330 340 ILQVMKGKNF IFNLGHGILP ETPPENIEFL TEYVRLYEKK NSNSTF

References

[1]

"Annotation of Ixodes scapularis." Ixodes scapularis Genome Project Consortium Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A. , Birren B., Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R. Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Wikel.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS815805 Genomic DNA. Translation: EEC11401.1.
RefSeq	XP_002401715.1. XM_002401671.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7PXS9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	ISCW020804-RA; ISCW020804-PA; ISCW020804.
GeneID	8032921.
KEGG	isc:IscW_ISCW020804.
VectorBase	ISCW020804. Ixodes scapularis.
Organism-specific databases
CTD	8032921.
Phylogenomic databases
GeneTree	EMGT00050000017769.
OMA	PRIHFGV.
OrthoDB	EOG4BNZTJ.
Family and domain databases
HAMAP	MF_00218. URO_D. [Tree]
InterPro	IPR006361. Uroporphyrinogen_deCO2ase_HemE. IPR000257. Uroporphyrinogen_deCOase. [Graphical view]
PANTHER	PTHR21091:SF2. HemE. 1 hit.
Pfam	PF01208. URO-D. 1 hit. [Graphical view]
TIGRFAMs	TIGR01464. HemE. 1 hit.
PROSITE	PS00906. UROD_1. 1 hit. PS00907. UROD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7PXS9_IXOSC

Accession

Primary (citable) accession number: B7PXS9

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	November 16, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)