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Protein
Submitted name:

Angiotensin-I converting enzyme, putative

Gene

IscW_ISCW005573

Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 2 Zn2+ ions per subunit.UniRule annotation

GO - Molecular functioni

  1. carboxypeptidase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. metallopeptidase activity Source: UniProtKB-KW
  4. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.005.

Names & Taxonomyi

Protein namesi
Submitted name:
Angiotensin-I converting enzyme, putativeImported (EC:3.4.15.1Imported)
Gene namesi
ORF Names:IscW_ISCW005573Imported
OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
Taxonomic identifieri6945 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes
ProteomesiUP000001555 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi6945.ISCW005573-PA.

Structurei

3D structure databases

ProteinModelPortaliB7PNY9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

eggNOGiNOG71044.
InParanoidiB7PNY9.
KOiK01283.
OMAiPFAYLMD.
OrthoDBiEOG7N37C7.
PhylomeDBiB7PNY9.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Fragment.

B7PNY9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
RMVSHAHAET YGMPCAPKVR PSALSLQIEQ SLVSGALYKE VWKNMTQFKW
60 70 80 90 100
TTFKDEQTRT IFRRFSTLGT SLLPEDKQKE YLKIVADMKG NHAAAKICPF
110 120 130 140 150
HRMTNQSDEC NVPLEPTIKN ILQDSRDYDE LLHVWNEWRR VSGRPLKAQY
160 170 180 190 200
SRYVELQNEA AKINGFDDAS GMWQESYECE DFEESIDQLW EQLQPLYKEL
210 220 230 240 250
HAYVRARLHA LHGDKVREDG PIPAHLLGQI HSQQWNSLYK FTQPFPGKPT
260 270 280 290 300
VDVTDAMLKM NMTPTEMFKL SEKFFTSMGL PPMPDSFWEK SVLEKPTDRE
310 320 330 340 350
IVCHASAWDF CGSGDVRIKQ CTQVKMDDLL VVHHEMGHIE YDLNYAKQPY
360 370 380 390 400
YFRAGANPGF HEAIGDTISL SVATPKHLKA VGLLEQSPED TETGINYLYK
410 420 430 440 450
IALDKVAGIP SMYVYDRWRW NVFKGKYQSE QLNKGWWDLL LKHQGICPGV
460 470 480 490 500
ARTPEDFDPP SKYHISASVP YIRYFASTVL QFQFYKALCE EANHKGPLHE
510
CDFYQSKEAG KLF
Length:513
Mass (Da):59,263
Last modified:February 10, 2009 - v1
Checksum:i5F06385AA091E2FA
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei513 – 5131Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS755121 Genomic DNA. Translation: EEC08311.1.
RefSeqiXP_002435481.1. XM_002435436.1.
UniGeneiIsc.7732.

Genome annotation databases

EnsemblMetazoaiISCW005573-RA; ISCW005573-PA; ISCW005573.
GeneIDi8051187.
KEGGiisc:IscW_ISCW005573.
VectorBaseiISCW005573. Ixodes scapularis.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS755121 Genomic DNA. Translation: EEC08311.1.
RefSeqiXP_002435481.1. XM_002435436.1.
UniGeneiIsc.7732.

3D structure databases

ProteinModelPortaliB7PNY9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6945.ISCW005573-PA.

Protein family/group databases

MEROPSiM02.005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiISCW005573-RA; ISCW005573-PA; ISCW005573.
GeneIDi8051187.
KEGGiisc:IscW_ISCW005573.
VectorBaseiISCW005573. Ixodes scapularis.

Organism-specific databases

CTDi8051187.

Phylogenomic databases

eggNOGiNOG71044.
InParanoidiB7PNY9.
KOiK01283.
OMAiPFAYLMD.
OrthoDBiEOG7N37C7.
PhylomeDBiB7PNY9.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WikelImported.

Entry informationi

Entry nameiB7PNY9_IXOSC
AccessioniPrimary (citable) accession number: B7PNY9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 7, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.