Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

8052446

Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei87NADUniRule annotation1
Binding sitei110SubstrateUniRule annotation1
Binding sitei145NAD; via amide nitrogenUniRule annotation1
Active sitei196Proton acceptorUniRule annotation1
Binding sitei260NADUniRule annotation1
Binding sitei287NAD; via amide nitrogenUniRule annotation1
Binding sitei289NADUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:8052446Imported
ORF Names:IscW_ISCW005254Imported
OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
Taxonomic identifieri6945 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes
Proteomesi
  • UP000001555 Componenti: Unassembled WGS sequence

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiB7PLJ6

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6945.ISCW005254-PA

Structurei

3D structure databases

ProteinModelPortaliB7PLJ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 164NAD_Gly3P_dh_NInterPro annotationAdd BLAST160
Domaini185 – 330NAD_Gly3P_dh_CInterPro annotationAdd BLAST146

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni260 – 261Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
InParanoidiB7PLJ6
KOiK00006
OMAiITMTVLM
OrthoDBiEOG091G0DO6
PhylomeDBiB7PLJ6

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

B7PLJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRGSAIAR IIGENVKKFD IFDHNVRMYV YEEIVDGRKL TEIINTQHEN
60 70 80 90 100
VKYLPGYKLP ENVSAVPEIV AACEDADVLV FVLPHKFIVP TCRPLVGKVK
110 120 130 140 150
PGAIGLSLIK GFDIAPGGGG IELISNVIHK LLNIEMCVLM GANLAREVAD
160 170 180 190 200
KKFCETTIGC RDPEKGVLLK KLIQTDYFRV TVVDDIPTIE VCGALKNIVA
210 220 230 240 250
VGAGFVDGLG YGDNTKAAVI RLGLMEMIAF ADTFYPGARL GTFFESCGVA
260 270 280 290 300
DLVTTCYGGR NRKVAEAFVR SNKSIEELEK EMLNGQKLQG PETAEEVFTM
310 320 330 340
LKNKNMLDRF PLFVAIHRIC SHEIAPSEMI QCIKNHPEHM
Length:340
Mass (Da):37,474
Last modified:February 10, 2009 - v1
Checksum:i41D65A10BF0B17BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABJB010263075 Genomic DNA No translation available.
ABJB010838203 Genomic DNA No translation available.
DS740929 Genomic DNA Translation: EEC07468.1
RefSeqiXP_002434644.1, XM_002434599.1
UniGeneiIsc.12848

Genome annotation databases

EnsemblMetazoaiISCW005254-RA; ISCW005254-PA; ISCW005254
GeneIDi8052446
KEGGiisc:IscW_ISCW005254
VectorBaseiISCW005254-RA; ISCW005254-PA; ISCW005254

Similar proteinsi

Entry informationi

Entry nameiB7PLJ6_IXOSC
AccessioniPrimary (citable) accession number: B7PLJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: June 20, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health