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B7PBZ1 (B7PBZ1_IXOSC) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Beta-1 subunit of nicotinic acetylcholine receptor, putative EMBL EEC04113.1
Gene names
ORF Names:IscW_ISCW003334 EMBL EEC04113.1
OrganismIxodes scapularis (Black-legged tick) (Deer tick)
Taxonomic identifier6945 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Chelicerata › Arachnida › Acari › Parasitiformes › Ixodida › Ixodoidea › Ixodidae › Ixodinae › Ixodes

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein By similarity RuleBase RU003585.

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification] RuleBase RU000687

Sequences

Sequence LengthMass (Da)Tools
B7PBZ1 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 2427FCC1B89A127D

FASTA55062,519
        10         20         30         40         50         60 
MRGREAREQP SPIDACGNVR ARREEGLLRE SSGEVRHSRL RSGRAMAFSA AGFAVLLLLA 

        70         80         90        100        110        120 
LLNVGCRGNP DAKRLYDDLM SSYNRLIRPV SNNSDRLTVK MGLKLSQLID VNIKNQIMTT 

       130        140        150        160        170        180 
NVWVNQEWSD HKLKWDPQEY GGVTELYVPA EQIWLPDIVL YNNADGNYEV TIMTKAIIHE 

       190        200        210        220        230        240 
DGRVVWNPPA IYKSSCQIDV QYFPFDKQDC FMKFGSWTYD GHQVDLKHLN EIQGTNIVPV 

       250        260        270        280        290        300 
GIDLSEFYLS VEWDIMAVPA MRREKFYSCC EQPYPDITFN ITLRRKTLFY TVNLIIPCVG 

       310        320        330        340        350        360 
ISCLSVLVFY LPSDSGEKVS LSISIMLSLT FFFLVLAEII PPTSLAMPLL GKYLVFTMIL 

       370        380        390        400        410        420 
VTVSVLVTIA VLNVHFRSPS THRMAPWVRR LFVHLMPRLL LMRPPQYRIE TDESSAAKPP 

       430        440        450        460        470        480 
QGGGSHGALH DDPLLLPEPL LVARPHGLHQ AAEPAGDQPS RDLERAIHNA MFIAQHIDNN 

       490        500        510        520        530        540 
DDFESIREDW KYVAMVLDRL FLWLFTLACV VGTAGIFLQA PSLYDQTDPI DVKFSQVARR 

       550 
MRIDYPWTDV

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References

[1]"Annotation of Ixodes scapularis."
Ixodes scapularis Genome Project Consortium
Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A. expand/collapse author list , Birren B., Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Wikel.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS680203 Genomic DNA. Translation: EEC04113.1.
RefSeqXP_002409079.1. XM_002409035.1.

3D structure databases

ProteinModelPortalB7PBZ1.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaISCW003334-RA; ISCW003334-PA; ISCW003334.
GeneID8027648.
KEGGisc:IscW_ISCW003334.
VectorBaseISCW003334. Ixodes scapularis.

Organism-specific databases

CTD8027648.

Phylogenomic databases

GeneTreeEMGT00050000005191.
OMATHSMPHW.
OrthoDBEOG4D2551.

Family and domain databases

InterProIPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
IPR002394. Nicotinic_acetylcholine_rcpt.
[Graphical view]
Gene3DG3DSA:2.70.170.10. Neur_chan_lig_bd. 1 hit.
KOK05312.
PANTHERPTHR18945. Neur_channel. 1 hit.
PfamPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSPR00254. NICOTINICR.
PR00252. NRIONCHANNEL.
SUPFAMSSF90112. Neu_channel_TM. 1 hit.
SSF63712. Neur_chan_LBD. 1 hit.
TIGRFAMsTIGR00860. LIC. 1 hit.
PROSITEPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7PBZ1_IXOSC
AccessionPrimary (citable) accession number: B7PBZ1
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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