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Protein
Submitted name:

Replication factor C large subunit, putative

Gene

IscW_ISCW002859

Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA clamp loader activity Source: InterPro
  3. DNA ligase (NAD+) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Replication factor C large subunit, putativeImported (EC:6.5.1.2Imported)
Gene namesi
ORF Names:IscW_ISCW002859Imported
OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
Taxonomic identifieri6945 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes
ProteomesiUP000001555: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. DNA replication factor C complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi6945.ISCW002859-PA.

Structurei

3D structure databases

ProteinModelPortaliB7P7N8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG5275.
InParanoidiB7P7N8.
KOiK10754.
OMAiASESICQ.
OrthoDBiEOG7N63M2.
PhylomeDBiB7P7N8.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR001357. BRCT_dom.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR012178. DNA_replication_fac_C_lsu.
IPR013725. DNA_replication_fac_RFC1_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF00533. BRCT. 1 hit.
PF08519. RFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF036578. RFC1. 1 hit.
SMARTiSM00382. AAA. 1 hit.
SM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52113. SSF52113. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B7P7N8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GSPGCLKGVT LVITGVLECI ERDDTRALLE RCGAKVTQSV SRNTTYLVAG
60 70 80 90 100
RDSGPAKLRK AEECKVKILD EDGFFELIES RSGGGSSTKK GGGAEPEGAL
110 120 130 140 150
PAEAAPEQGA PSKKRKAEAD DEPAETKIPR VSVSPPEKAD VDAAAASTSK
160 170 180 190 200
TSPARLPSAV RFKPSLITLT CWEQVTSPLF RFHGCQQGQM WVDRYRPQTT
210 220 230 240 250
KQIIGQQGDK SNCHKLRLWL QNWHKSRAGP KRPPPKWGGG GGDGSAFKAA
260 270 280 290 300
LLSGAPGVGK TTTANLVARE AGFSVLELNA SDTRSKKSLK QEVAELLGNQ
310 320 330 340 350
TLTGATTARA REGLSSKHML IMDEVDGMAG NQDRGGVQEL IALIKSTRIP
360 370 380 390 400
IVCICNDRSH PKMRSLVNYC FDLRFYRPQV KQIQAAMMSI ACKEGLSVTP
410 420 430 440 450
AVVQEIIMAS NQDVRQVLHN LSLWTARTKG ISSEQVKADT GKGTKDIRLG
460 470 480 490 500
PFDVVRKILS SAEGGQSLSL GEKSALFFHD YSMVPMFVQD NYIHVQPLAA
510 520 530 540 550
QGDKKRHLRL LVEASESICQ GDLIERQIRS CGSWSLLPMQ AFFSSVIPGE
560 570 580 590 600
LMRGQLREMV SFPAWFGKNS SLGKRQRLLQ ELYMHMHTRV SANRTQLHMD
610 620 630 640 650
YLSPLLHSLT QPLIAKGADG VPSTLGLMGH YFLQRADLDT VAELSLWPGM
660 670 680 690 700
KDPWSRVDSK VKAALTRALN KEGFMTPYAT DDMVKKKGKR GSSKAAKGTA

EPEEED
Length:706
Mass (Da):77,009
Last modified:February 10, 2009 - v1
Checksum:i37FDD4007BCB9EBB
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei706 – 7061Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS652836 Genomic DNA. Translation: EEC02610.1.
RefSeqiXP_002399407.1. XM_002399366.1.
UniGeneiIsc.10978.

Genome annotation databases

EnsemblMetazoaiISCW002859-RA; ISCW002859-PA; ISCW002859.
GeneIDi8025839.
KEGGiisc:IscW_ISCW002859.
VectorBaseiISCW002859. Ixodes scapularis.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS652836 Genomic DNA. Translation: EEC02610.1.
RefSeqiXP_002399407.1. XM_002399366.1.
UniGeneiIsc.10978.

3D structure databases

ProteinModelPortaliB7P7N8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6945.ISCW002859-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiISCW002859-RA; ISCW002859-PA; ISCW002859.
GeneIDi8025839.
KEGGiisc:IscW_ISCW002859.
VectorBaseiISCW002859. Ixodes scapularis.

Organism-specific databases

CTDi8025839.

Phylogenomic databases

eggNOGiCOG5275.
InParanoidiB7P7N8.
KOiK10754.
OMAiASESICQ.
OrthoDBiEOG7N63M2.
PhylomeDBiB7P7N8.

Family and domain databases

Gene3Di3.40.50.10190. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR001357. BRCT_dom.
IPR008921. DNA_pol3_clamp-load_cplx_C.
IPR012178. DNA_replication_fac_C_lsu.
IPR013725. DNA_replication_fac_RFC1_C.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00004. AAA. 1 hit.
PF00533. BRCT. 1 hit.
PF08519. RFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF036578. RFC1. 1 hit.
SMARTiSM00382. AAA. 1 hit.
SM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF48019. SSF48019. 1 hit.
SSF52113. SSF52113. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WikelImported.

Entry informationi

Entry nameiB7P7N8_IXOSC
AccessioniPrimary (citable) accession number: B7P7N8
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 7, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.