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Protein
Submitted name:

Histone-lysine N-methyltransferase, setb1, putative

Gene

IscW_ISCW001711

Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Histone-lysine N-methyltransferase, setb1, putativeImported (EC:2.1.1.43Imported)
Gene namesi
ORF Names:IscW_ISCW001711Imported
OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
Taxonomic identifieri6945 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes
Proteomesi
  • UP000001555 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Nucleus UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi6945.ISCW001711-PA.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini311 – 37969MBD (methyl-CpG-binding)InterPro annotationAdd
BLAST
Domaini441 – 51272Pre-SETInterPro annotationAdd
BLAST
Domaini515 – 719205SETInterPro annotationAdd
BLAST
Domaini728 – 74417Post-SETInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG1141. Eukaryota.
COG2940. LUCA.
InParanoidiB7P544.
KOiK11421.
OMAiERPMVKL.
OrthoDBiEOG7ZD1TG.
PhylomeDBiB7P544.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7P544-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYHIKFEARK PNAGMRQSKW FSPRELAYAD RPPVVLPIGT RVVATYTDES
60 70 80 90 100
WNQRQSLYAG LIAEPPKPLN RYRYLVFFDD GYAQYVHIDK VFVMCGTSKT
110 120 130 140 150
GVWDDMYRDV RDFVKTYLQK YPERPMLRMR KGQTVKTEWN GKWWMARVLT
160 170 180 190 200
VDASLAKMAF EADDRTEWIY RGSTRFAPLY TALSHTAQQS AAPGGRVRRQ
210 220 230 240 250
NLVPATGKQH RPFVEYTREA DESSSAATAT KGDETKKAAA AITASDKRNA
260 270 280 290 300
ARKSAAQDRK SAPWEEPEVA ASQAGTRELR CVEGSSTYRR KIYLEHECSP
310 320 330 340 350
TCVEPDDPEK LVGHNPLSIP CLMGWERQLA KLSKKTKRRV FYTAPCGRRL
360 370 380 390 400
RNIAEVAQYL VLSKCLLTVD QFCFDSAVNV FAHFEPQTVL SSLKDLTYGK
410 420 430 440 450
ELVPVTCINS LSTEYPSYIE YSATRYPGKG VTLNLDKEFL CGCDCEDDCQ
460 470 480 490 500
DRDKCSCQQL TVAATGALPS GVNPSAGYRF RRLHEPLITG VYECNAQCKC
510 520 530 540 550
SKRCQNRVVQ NGLRCRLQVF RTEKRGWGVR CLDDLPQGCF VCIYAGQLLT
560 570 580 590 600
EQGANEDGNQ YGDEYLAELD HIEVVEKQKE GYESDVVNSE EEEEGDEEAA
610 620 630 640 650
VSDYDDDSVE KSQRTPKKKE KNKAGKGDGK VKTGPLESPG IGGKRLRFPP
660 670 680 690 700
TRSFFNEEYC YIMDAKNCGN IGRYLNHSCC PNVYVQNVFV DSHDLRFPWV
710 720 730 740
AFFASRYIRA GMELTWDYNY DVGSVPERVM YCQCGAEECR GRLI
Length:744
Mass (Da):84,455
Last modified:February 10, 2009 - v1
Checksum:iF4C71E57B27493F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS639181 Genomic DNA. Translation: EEC01716.1.
RefSeqiXP_002406985.1. XM_002406941.1.
UniGeneiIsc.8223.

Genome annotation databases

EnsemblMetazoaiISCW001711-RA; ISCW001711-PA; ISCW001711.
GeneIDi8024753.
KEGGiisc:IscW_ISCW001711.
VectorBaseiISCW001711. Ixodes scapularis.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS639181 Genomic DNA. Translation: EEC01716.1.
RefSeqiXP_002406985.1. XM_002406941.1.
UniGeneiIsc.8223.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6945.ISCW001711-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiISCW001711-RA; ISCW001711-PA; ISCW001711.
GeneIDi8024753.
KEGGiisc:IscW_ISCW001711.
VectorBaseiISCW001711. Ixodes scapularis.

Organism-specific databases

CTDi8024753.

Phylogenomic databases

eggNOGiKOG1141. Eukaryota.
COG2940. LUCA.
InParanoidiB7P544.
KOiK11421.
OMAiERPMVKL.
OrthoDBiEOG7ZD1TG.
PhylomeDBiB7P544.

Family and domain databases

Gene3Di3.30.890.10. 1 hit.
InterProiIPR016177. DNA-bd_dom.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WikelImported.

Entry informationi

Entry nameiB7P544_IXOSC
AccessioniPrimary (citable) accession number: B7P544
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: April 13, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.