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B7P544 (B7P544_IXOSC) Unreviewed, UniProtKB/TrEMBL

Last modified March 6, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Histone-lysine N-methyltransferase, setb1, putative EMBL EEC01716.1
EC=2.1.1.43 EMBL EEC01716.1
Gene names
ORF Names:IscW_ISCW001711 EMBL EEC01716.1
OrganismIxodes scapularis (Black-legged tick) (Deer tick) [Reference proteome]
Taxonomic identifier6945 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Ecdysozoa › Arthropoda › Chelicerata › Arachnida › Acari › Parasitiformes › Ixodida › Ixodoidea › Ixodidae › Ixodinae › Ixodes

Protein attributes

Sequence length744 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214

S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine.

Subcellular location

Nucleus By similarity.

Sequence similarities

Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214

Contains 1 post-SET domain. RuleBase RU004541

Contains 1 pre-SET domain. SAAS SAAS001214

Sequences

Sequence LengthMass (Da)Tools
B7P544 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: F4C71E57B27493F3

FASTA74484,455
        10         20         30         40         50         60 
MYHIKFEARK PNAGMRQSKW FSPRELAYAD RPPVVLPIGT RVVATYTDES WNQRQSLYAG 

        70         80         90        100        110        120 
LIAEPPKPLN RYRYLVFFDD GYAQYVHIDK VFVMCGTSKT GVWDDMYRDV RDFVKTYLQK 

       130        140        150        160        170        180 
YPERPMLRMR KGQTVKTEWN GKWWMARVLT VDASLAKMAF EADDRTEWIY RGSTRFAPLY 

       190        200        210        220        230        240 
TALSHTAQQS AAPGGRVRRQ NLVPATGKQH RPFVEYTREA DESSSAATAT KGDETKKAAA 

       250        260        270        280        290        300 
AITASDKRNA ARKSAAQDRK SAPWEEPEVA ASQAGTRELR CVEGSSTYRR KIYLEHECSP 

       310        320        330        340        350        360 
TCVEPDDPEK LVGHNPLSIP CLMGWERQLA KLSKKTKRRV FYTAPCGRRL RNIAEVAQYL 

       370        380        390        400        410        420 
VLSKCLLTVD QFCFDSAVNV FAHFEPQTVL SSLKDLTYGK ELVPVTCINS LSTEYPSYIE 

       430        440        450        460        470        480 
YSATRYPGKG VTLNLDKEFL CGCDCEDDCQ DRDKCSCQQL TVAATGALPS GVNPSAGYRF 

       490        500        510        520        530        540 
RRLHEPLITG VYECNAQCKC SKRCQNRVVQ NGLRCRLQVF RTEKRGWGVR CLDDLPQGCF 

       550        560        570        580        590        600 
VCIYAGQLLT EQGANEDGNQ YGDEYLAELD HIEVVEKQKE GYESDVVNSE EEEEGDEEAA 

       610        620        630        640        650        660 
VSDYDDDSVE KSQRTPKKKE KNKAGKGDGK VKTGPLESPG IGGKRLRFPP TRSFFNEEYC 

       670        680        690        700        710        720 
YIMDAKNCGN IGRYLNHSCC PNVYVQNVFV DSHDLRFPWV AFFASRYIRA GMELTWDYNY 

       730        740 
DVGSVPERVM YCQCGAEECR GRLI

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References

[1]"Annotation of Ixodes scapularis."
Ixodes scapularis Genome Project Consortium
Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A. expand/collapse author list , Birren B., Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.
Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Wikel.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS639181 Genomic DNA. Translation: EEC01716.1.
RefSeqXP_002406985.1. XM_002406941.1.
UniGeneIsc.8223.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaISCW001711-RA; ISCW001711-PA; ISCW001711.
GeneID8024753.
KEGGisc:IscW_ISCW001711.
VectorBaseISCW001711. Ixodes scapularis.

Organism-specific databases

CTD8024753.

Phylogenomic databases

eggNOGCOG2940.
KOK11421.
OMAQCWQLTI.
OrthoDBEOG4THT82.
PhylomeDBB7P544.

Family and domain databases

Gene3D3.30.890.10. 1 hit.
InterProIPR016177. DNA-bd_integrase-typ.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTSM00317. SET. 1 hit.
[Graphical view]
SUPFAMSSF54171. DNA-binding_integrase-type. 1 hit.
PROSITEPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7P544_IXOSC
AccessionPrimary (citable) accession number: B7P544
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: March 6, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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