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B7NPS4

- GLK_ECO7I

UniProt

B7NPS4 - GLK_ECO7I

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Protein
Glucokinase
Gene
glk, ECIAI39_2533
Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL585057:GJ8I-2608-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:ECIAI39_2533
OrganismiEscherichia coli O7:K1 (strain IAI39 / ExPEC)
Taxonomic identifieri585057 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000749: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlucokinaseUniRule annotation
PRO_1000127701Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi585057.ECIAI39_2533.

Structurei

3D structure databases

ProteinModelPortaliB7NPS4.
SMRiB7NPS4. Positions 2-321.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiPRETQLW.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

B7NPS4-1 [UniParc]FASTAAdd to Basket

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MTKYALVGDV GGTNARLALC DIASGEISQA KTYSGLDYPS LEAVIRVYLE    50
EHKVEVKDGC IAIACPITGD WVAMTNHTWA FSIAEMKKNL GFSHLEIIND 100
FTAVSMAIPM LKKEHLIQFG GAEPIEGKPI AVYGAGTGLG VAHLVHVDKR 150
WVSLPGEGGH VDFAPNSEEE GIILEILRAE IGHVSAERVL SGPGLVNLYR 200
AIVKADNRLP ENLKPKDITE RALADSCTDC RRALSLFCVI MGRFGGNLAL 250
NLGTFGGVFI AGGIVPRFLE FFKASGFRAA FEDKGRFKEY VHDIPVYLIV 300
HDNPGLLGSG AHLRQTLGHI L 321
Length:321
Mass (Da):34,723
Last modified:February 10, 2009 - v1
Checksum:iA0ABCC4ECB5BC6B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928164 Genomic DNA. Translation: CAR18657.1.
RefSeqiYP_002408485.1. NC_011750.1.

Genome annotation databases

EnsemblBacteriaiCAR18657; CAR18657; ECIAI39_2533.
GeneIDi7154473.
KEGGiect:ECIAI39_2533.
PATRICi18333829. VBIEscCol51957_2637.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928164 Genomic DNA. Translation: CAR18657.1 .
RefSeqi YP_002408485.1. NC_011750.1.

3D structure databases

ProteinModelPortali B7NPS4.
SMRi B7NPS4. Positions 2-321.
ModBasei Search...

Protein-protein interaction databases

STRINGi 585057.ECIAI39_2533.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR18657 ; CAR18657 ; ECIAI39_2533 .
GeneIDi 7154473.
KEGGi ect:ECIAI39_2533.
PATRICi 18333829. VBIEscCol51957_2637.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi PRETQLW.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci ECOL585057:GJ8I-2608-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IAI39 / ExPEC.

Entry informationi

Entry nameiGLK_ECO7I
AccessioniPrimary (citable) accession number: B7NPS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: June 11, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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