Reviewed, UniProtKB/Swiss-Prot B7NM39 (SSUD_ECO7I)

Names and origin

Protein names

Recommended name:
    Alkanesulfonate monooxygenase
    EC=1.14.14.5
Alternative name(s):
    FMNH2-dependent aliphatic sulfonate monooxygenase

Gene names

Name:	ssuD
Ordered Locus Names:	ECIAI39_2212

Organism

Escherichia coli O7:K1 (strain IAI39 / ExPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

585057 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the desulfonation of aliphatic sulfonates By similarity. HAMAP MF_01229
Catalytic activity	An alkanesufonate (R-CH(2)-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O. HAMAP MF_01229
Subunit structure	Homotetramer By similarity. HAMAP MF_01229
Miscellaneous	FMNH2 which is absolutely required for this enzymatic reaction, is provided by ssuE By similarity. HAMAP MF_01229
Sequence similarities	Belongs to the ssuD family.

Ontologies

Keywords
Ligand	FMN
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alkanesulfonate monooxygenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	Alkanesulfonate monooxygenase HAMAP MF_01229		PRO_1000139618

Sequences

	Sequence		Length	Mass (Da)
	B7NM39-1 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 032FF2199DC0D613	FASTA	381	41,716
	10 20 30 40 50 60 MSLNMFWFLP THGDGHYLGT EEGSRPVDHG YLQQIAQAAD RLGYTGVLIP TGRSCEDAWL 70 80 90 100 110 120 VEASMIPVTQ RLKFLVALRP SVTSPTVAAR QAATLDRLSN GRALFNLVTG SDPQELAGDG 130 140 150 160 170 180 VFLDHSERYE ASAEFTQVWR RLLLGETVDF NGKHIHVRGA KLLFPPIQQP YPPLYFGGSS 190 200 210 220 230 240 DVAQELAAEQ VDLYLTWGEP PELVKEKIEQ VRAKAAAHGR KIRFGIRLHV IVRETNDEAW 250 260 270 280 290 300 QAAERLISHL DDETIAKAQA AFARTDSVGQ QRMAALHNGK RDNLEISPNL WAGVGLVRGG 310 320 330 340 350 360 AGTALVGDGP TVAARINEYA ALGIDSFVLS GYPHLEEAYR VGELLFPHLD VAIPEIPQPQ 370 380 PLNPQGEAVA NDFIPRNVAQ S

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed: 19165319] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928164 Genomic DNA. Translation: CAR18339.1.
RefSeq	YP_002408175.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	7152911.
GenomeReviews	Gene locus ECIAI39_2212 in contig CU928164_GR.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG639644.
OMA	NIFWFLP.
Family and domain databases
HAMAP	MF_01229. Alkanesulf_monooxygen. [Tree]
InterPro	IPR019911. Alkanesulphonate_mOase_FMN-dep. IPR011251. Luciferase-like. [Graphical view]
Gene3D	G3DSA:3.20.20.30. Luciferase_like. 1 hit.
TIGRFAMs	TIGR03565. Alk_sulf_monoox. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SSUD_ECO7I

Accession

Primary (citable) accession number: B7NM39

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	February 9, 2010
This is version 10 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)