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Protein

Cyanate hydratase

Gene

cynS

Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.UniRule annotation

Catalytic activityi

Cyanate + HCO3- + 2 H+ = NH3 + 2 CO2.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei96 – 961UniRule annotation
Active sitei99 – 991UniRule annotation
Active sitei122 – 1221UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciECOL585057:GJ8I-348-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyanate hydrataseUniRule annotation (EC:4.2.1.104UniRule annotation)
Short name:
CyanaseUniRule annotation
Alternative name(s):
Cyanate hydrolaseUniRule annotation
Cyanate lyaseUniRule annotation
Gene namesi
Name:cynSUniRule annotation
Ordered Locus Names:ECIAI39_0338
OrganismiEscherichia coli O7:K1 (strain IAI39 / ExPEC)
Taxonomic identifieri585057 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000749 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 156156Cyanate hydratasePRO_1000128224Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliB7NK15.
SMRiB7NK15. Positions 1-156.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyanase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000043436.
KOiK01725.
OMAiPMKDVIQ.

Family and domain databases

CDDicd00559. Cyanase_C. 1 hit.
Gene3Di1.10.260.40. 1 hit.
3.30.1160.10. 1 hit.
HAMAPiMF_00535. Cyanate_hydrat. 1 hit.
InterProiIPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02560. Cyanate_lyase. 1 hit.
[Graphical view]
PIRSFiPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSiPR01693. CYANASE.
SMARTiSM01116. Cyanate_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsiTIGR00673. cynS. 1 hit.

Sequencei

Sequence statusi: Complete.

B7NK15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQSQINRNI RLDLADAILL SKAKKDLSFA EIADGTGLAE AFVTAALLGQ
60 70 80 90 100
QALPADAARL VGAKLDLDED AILLLQMIPL RGCIDDRIPT DPTMYRFYEM
110 120 130 140 150
LQVYGTTLKA LVHEKFGDGI ISAINFKLDV KKVADPEGGE RAVITLDGKY

LPTKPF
Length:156
Mass (Da):17,033
Last modified:March 24, 2009 - v1
Checksum:i829E903B262F230C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928164 Genomic DNA. Translation: CAR16478.1.
RefSeqiWP_000616241.1. NC_011750.1.
YP_002406380.1. NC_011750.1.

Genome annotation databases

EnsemblBacteriaiCAR16478; CAR16478; ECIAI39_0338.
GeneIDi7151049.
KEGGiect:ECIAI39_0338.
PATRICi18329204. VBIEscCol51957_0365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928164 Genomic DNA. Translation: CAR16478.1.
RefSeqiWP_000616241.1. NC_011750.1.
YP_002406380.1. NC_011750.1.

3D structure databases

ProteinModelPortaliB7NK15.
SMRiB7NK15. Positions 1-156.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR16478; CAR16478; ECIAI39_0338.
GeneIDi7151049.
KEGGiect:ECIAI39_0338.
PATRICi18329204. VBIEscCol51957_0365.

Phylogenomic databases

HOGENOMiHOG000043436.
KOiK01725.
OMAiPMKDVIQ.

Enzyme and pathway databases

BioCyciECOL585057:GJ8I-348-MONOMER.

Family and domain databases

CDDicd00559. Cyanase_C. 1 hit.
Gene3Di1.10.260.40. 1 hit.
3.30.1160.10. 1 hit.
HAMAPiMF_00535. Cyanate_hydrat. 1 hit.
InterProiIPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02560. Cyanate_lyase. 1 hit.
[Graphical view]
PIRSFiPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSiPR01693. CYANASE.
SMARTiSM01116. Cyanate_lyase. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsiTIGR00673. cynS. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCYNS_ECO7I
AccessioniPrimary (citable) accession number: B7NK15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 24, 2009
Last modified: September 7, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.