Reviewed, UniProtKB/Swiss-Prot B7NER6 (SECB_ECOLU)

Names and origin

Protein names

Recommended name:
    Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	ECUMN_4126

Organism

Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

585056 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	155 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity. HAMAP MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity. HAMAP MF_00821
Subcellular location	Cytoplasm By similarity HAMAP MF_00821.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: HAMAP protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: HAMAP transmembrane transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 155	155	Protein-export protein secB HAMAP MF_00821		PRO_1000195321

Sequences

	Sequence		Length	Mass (Da)
	B7NER6-1 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: 00514C5F393A643D	FASTA	155	17,277
	10 20 30 40 50 60 MSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ LADDVYEVVL 70 80 90 100 110 120 RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA YCPNILFPYA RECITSMVSR 130 140 150 GTFPQLNLAP VNFDALFMNY LQQQAGEGTE EHQDA

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed: 19165319] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928163 Genomic DNA. Translation: CAR15267.1.
RefSeq	YP_002414765.1.
3D structure databases
SMR	B7NER6. Positions 9-144.
ModBase	Search...
Genome annotation databases
GeneID	7156607.
GenomeReviews	Gene locus ECUMN_4126 in contig CU928163_GR.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	GFPPLMI.
Family and domain databases
HAMAP	MF_00821. SecB. [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
TIGRFAMs	TIGR00809. secB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_ECOLU

Accession

Primary (citable) accession number: B7NER6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 24, 2009
Last modified:	February 9, 2010
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)