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B7N8V6

- ACPH_ECOLU

UniProt

B7N8V6 - ACPH_ECOLU

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Protein

Acyl carrier protein phosphodiesterase

Gene
acpH, ECUMN_0442
Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP By similarity.UniRule annotation

Catalytic activityi

Holo-[acyl-carrier-protein] + H2O = 4'-phosphopantetheine + apo-[acyl-carrier-protein].UniRule annotation

GO - Molecular functioni

  1. [acyl-carrier-protein] phosphodiesterase activity Source: UniProtKB-EC

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl carrier protein phosphodiesterase (EC:3.1.4.14)
Short name:
ACP phosphodiesterase
Gene namesi
Name:acpH
Ordered Locus Names:ECUMN_0442
OrganismiEscherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Taxonomic identifieri585056 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000007097: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 193193Acyl carrier protein phosphodiesteraseUniRule annotationPRO_1000188805Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi585056.ECUMN_0442.

Structurei

3D structure databases

ProteinModelPortaliB7N8V6.

Family & Domainsi

Sequence similaritiesi

Belongs to the AcpH family.

Phylogenomic databases

eggNOGiCOG3124.
HOGENOMiHOG000275880.
KOiK08682.
OMAiWLHRQID.
OrthoDBiEOG6K6V7H.

Family and domain databases

HAMAPiMF_01950. AcpH.
InterProiIPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view]
PfamiPF04336. DUF479. 1 hit.
[Graphical view]
PIRSFiPIRSF011489. DUF479. 1 hit.

Sequencei

Sequence statusi: Complete.

B7N8V6-1 [UniParc]FASTAAdd to Basket

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MNFLAHLHLA HLAESSLSGN LLADFVRGNP EESFPPDVVA GIHMHRRIDV    50
LTDNLPEVRE AREWFRSETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE 100
FVCYAREQVM TILPDSPPRF INLNNYLWSE QWLVRYRDMD FIQNVLNGMA 150
SRRPRLDALR DSWYDLDAHY DALETRFWQF YPRMMAQASR KAL 193
Length:193
Mass (Da):22,961
Last modified:March 24, 2009 - v1
Checksum:i0DE6F0CE01D6C523
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928163 Genomic DNA. Translation: CAR11657.1.
RefSeqiYP_002411205.1. NC_011751.1.

Genome annotation databases

EnsemblBacteriaiCAR11657; CAR11657; ECUMN_0442.
GeneIDi7154675.
KEGGieum:ECUMN_0442.
PATRICi18440121. VBIEscCol32010_0645.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928163 Genomic DNA. Translation: CAR11657.1 .
RefSeqi YP_002411205.1. NC_011751.1.

3D structure databases

ProteinModelPortali B7N8V6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 585056.ECUMN_0442.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR11657 ; CAR11657 ; ECUMN_0442 .
GeneIDi 7154675.
KEGGi eum:ECUMN_0442.
PATRICi 18440121. VBIEscCol32010_0645.

Phylogenomic databases

eggNOGi COG3124.
HOGENOMi HOG000275880.
KOi K08682.
OMAi WLHRQID.
OrthoDBi EOG6K6V7H.

Family and domain databases

HAMAPi MF_01950. AcpH.
InterProi IPR007431. ACP_phosphodiesterase.
IPR023491. ACP_phosphodiesterase_gpbac.
[Graphical view ]
Pfami PF04336. DUF479. 1 hit.
[Graphical view ]
PIRSFi PIRSF011489. DUF479. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UMN026 / ExPEC.

Entry informationi

Entry nameiACPH_ECOLU
AccessioniPrimary (citable) accession number: B7N8V6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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