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B7N528 (YDIB_ECOLU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Quinate/shikimate dehydrogenase
EC=1.1.1.282
Alternative name(s):
NAD-dependent shikimate 5-dehydrogenase 2
Gene names
Name:ydiB
Ordered Locus Names:ECUMN_1981
OrganismEscherichia coli O17:K52:H18 (strain UMN026 / ExPEC) [Complete proteome] [HAMAP]
Taxonomic identifier585056 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H. HAMAP MF_01578

Shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H. HAMAP MF_01578

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP MF_01578

Subunit structure

Homodimer By similarity. HAMAP MF_01578

Sequence similarities

Belongs to the shikimate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288Quinate/shikimate dehydrogenase HAMAP MF_01578
PRO_1000147552

Regions

Nucleotide binding131 – 1355NAD By similarity
Nucleotide binding155 – 1584NAD By similarity
Nucleotide binding255 – 2595NAD By similarity

Sites

Active site711Proton acceptor Potential
Binding site1071Substrate By similarity
Binding site2051NAD; via amide nitrogen By similarity
Binding site2351NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
B7N528 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: C2CE415E034D0A5A

FASTA28831,218
        10         20         30         40         50         60 
MDVTAKYELI GLMAYPIRHS LSPEMQNKAL EKAGLSFTYM AFEVDNDSFP GAIEGLKALK 

        70         80         90        100        110        120 
MRGTGVSMPN KQLACEYVDE LTPAAKLVGA INTIVNDDGY LRGYNTDGTG HIRAIKESGF 

       130        140        150        160        170        180 
DIKGKTMVLL GAGGASTAIG AQGAIEGLKE IKLFNRRDEF FDKALAFAQR VNENTDCVVT 

       190        200        210        220        230        240 
VTDLADQQAF AEALASADIL TNGTKVGMKP LENESLVNDI SLLHPGLLVT ECVYNPHMTK 

       250        260        270        280 
LLQQAQQAGC KTIDGYGMLL WQGAEQFTLW TGKDFPLEYV KQVMGFGA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU928163 Genomic DNA. Translation: CAR13177.1.
RefSeqYP_002412709.1. NC_011751.1.

3D structure databases

ProteinModelPortalB7N528.
SMRB7N528. Positions 1-288.
ModBaseSearch...

Protein-protein interaction databases

STRINGB7N528.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000119029; EBESCP00000111460; EBESCG00000119703.
GeneID7158701.
GenomeReviewsGene locus ECUMN_1981 in contig CU928163_GR.
PATRIC18443210. VBIEscCol32010_2167.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000010797.
HOGENOMHBG553408.
OMAGSFAMPA.
ProtClustDBPRK12749.

Enzyme and pathway databases

BioCycECOL585056:ECUMN_1981-MONOMER.

Family and domain databases

HAMAPMF_01578. Shikimate_DH_YdiB.
[Tree]
InterProIPR016040. NAD(P)-bd_dom.
IPR022872. Quinate/Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PfamPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYDIB_ECOLU
AccessionPrimary (citable) accession number: B7N528
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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