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Protein

Cell division protein ZapA

Gene

zapA

Organism
Escherichia coli O81 (strain ED1a)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.UniRule annotation

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Septation

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein ZapAUniRule annotation
Alternative name(s):
Z ring-associated protein ZapAUniRule annotation
Gene namesi
Name:zapAUniRule annotation
Ordered Locus Names:ECED1_3369
OrganismiEscherichia coli O81 (strain ED1a)
Taxonomic identifieri585397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000748 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Localizes at mid-cell.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001895111 – 109Cell division protein ZapAAdd BLAST109

Interactioni

Subunit structurei

Homodimer. Interacts with FtsZ.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7MZK7.
SMRiB7MZK7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili21 – 99UniRule annotationAdd BLAST79

Sequence similaritiesi

Belongs to the ZapA family. Type 1 subfamily.UniRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000263522.
KOiK09888.
OMAiNICYELH.

Family and domain databases

HAMAPiMF_02012. ZapA_type1. 1 hit.
InterProiView protein in InterPro
IPR007838. Cell_div_ZapA-like.
IPR023771. Cell_div_ZapA_eubact.
PfamiView protein in Pfam
PF05164. ZapA. 1 hit.
SUPFAMiSSF102829. SSF102829. 1 hit.

Sequencei

Sequence statusi: Complete.

B7MZK7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAQPVDIQI FGRSLRVNCP PDQRDALNQA ADDLNQRLQD LKERTRVTNT
60 70 80 90 100
EQLVFIAALN ISYELAQEKA KTRDYAASME QRIRMLQQTI EQALLEQGRI

TEKTNQNFE
Length:109
Mass (Da):12,594
Last modified:April 14, 2009 - v1
Checksum:i26777CC2B2B71148
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928162 Genomic DNA. Translation: CAR09525.2.
RefSeqiWP_001276008.1. NC_011745.1.

Genome annotation databases

EnsemblBacteriaiCAR09525; CAR09525; ECED1_3369.
KEGGiecq:ECED1_3369.

Similar proteinsi

Entry informationi

Entry nameiZAPA_ECO81
AccessioniPrimary (citable) accession number: B7MZK7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: April 14, 2009
Last modified: June 7, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families