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Protein

Transcriptional regulatory protein RcsA

Gene

rcsA

Organism
Escherichia coli O81 (strain ED1a)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi155 – 17420H-T-H motifUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sensory transductionUniRule annotation, Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Enzyme and pathway databases

BioCyciECOL585397:GJCU-2245-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein RcsAUniRule annotation
Gene namesi
Name:rcsAUniRule annotationImported
Ordered Locus Names:ECED1_2218Imported
OrganismiEscherichia coli O81 (strain ED1a)Imported
Taxonomic identifieri585397 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000748 Componenti: Chromosome

Interactioni

Subunit structurei

Interacts with RcsB.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7MWD9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini131 – 19666HTH luxR-typeUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the RcsA family.UniRule annotation
Contains 1 HTH luxR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG2771.
HOGENOMiHOG000121332.
KOiK07781.
OMAiTIIMDSC.
OrthoDBiEOG65TRRN.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00982. RcsA.
InterProiIPR030866. RcsA.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7MWD9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTIIMDLCS YTRLGLTGYL LSRGVKKREI NDIETVDDLA IACDSQRPSV
60 70 80 90 100
VFINEDCFIH DASNSQHIKH IINQHPNTLF IVFMAIANVH FDEYLLVRKN
110 120 130 140 150
LLISSKSIKP ESLDDILGDI LKKETTITSF LNMPTLSLSR TESSMLRMWM
160 170 180 190 200
AGQGTIQISD QMNIKAKTVS SHKGNIKRKI KTHNKQVIYH VVRLTDNVTN

GIFVNMR
Length:207
Mass (Da):23,521
Last modified:April 14, 2009 - v1
Checksum:i70684B16002FD395
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928162 Genomic DNA. Translation: CAR08405.2.
RefSeqiWP_000103987.1. NC_011745.1.

Genome annotation databases

EnsemblBacteriaiCAR08405; CAR08405; ECED1_2218.
KEGGiecq:ECED1_2218.
PATRICi38488484. VBIEscCol8292_2244.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928162 Genomic DNA. Translation: CAR08405.2.
RefSeqiWP_000103987.1. NC_011745.1.

3D structure databases

ProteinModelPortaliB7MWD9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAR08405; CAR08405; ECED1_2218.
KEGGiecq:ECED1_2218.
PATRICi38488484. VBIEscCol8292_2244.

Phylogenomic databases

eggNOGiCOG2771.
HOGENOMiHOG000121332.
KOiK07781.
OMAiTIIMDSC.
OrthoDBiEOG65TRRN.

Enzyme and pathway databases

BioCyciECOL585397:GJCU-2245-MONOMER.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00982. RcsA.
InterProiIPR030866. RcsA.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
PROSITEiPS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ED1aImported.

Entry informationi

Entry nameiB7MWD9_ECO81
AccessioniPrimary (citable) accession number: B7MWD9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 14, 2009
Last sequence update: April 14, 2009
Last modified: June 24, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.