B7MUT4 (B7MUT4_ECO81) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Altronate oxidoreductase HAMAP MF_00670
EC=1.1.1.58 HAMAP MF_00670

Alternative name(s):
Tagaturonate dehydrogenase HAMAP MF_00670
Tagaturonate reductase HAMAP MF_00670

Gene names

Name:	uxaB HAMAP MF_00670 EMBL CAR07850.2
Ordered Locus Names:	ECED1_1653

Organism

Escherichia coli O81 (strain ED1a) [Complete proteome] [HAMAP]

Taxonomic identifier

585397 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	495 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-altronate + NAD+ = D-tagaturonate + NADH. HAMAP MF_00670
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00670
Sequence similarities	Belongs to the mannitol dehydrogenase family. UxaB subfamily. HAMAP MF_00670

Ontologies

Keywords
Ligand	NAD HAMAP MF_00670
Molecular function	Oxidoreductase HAMAP MF_00670 EMBL CAR07850.2
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro tagaturonate reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	30 – 41	12	NAD By similarity HAMAP MF_00670

Sequences

	Sequence		Length	Mass (Da)
	B7MUT4 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 22DC4CA60023D2FA	FASTA	495	56,130
	10 20 30 40 50 60 MAVAMDNAIL ENILRQVRRD FPGAQYPERI IQFGEGNFLR AFVDWQIDLL NEHTDLNSGV 70 80 90 100 110 120 VVVRPIETSF PPSLSTQDGL YTTIIRGLNE KGEAVSDARL IRSVNREISV YSEYDEFLKL 130 140 150 160 170 180 AHNPEMRFVF SNTTEAGISY HAGDKFDDAP AVSYPAKLTR LLFERFSHFN GALDKGWIII 190 200 210 220 230 240 PCELIDYNGD ALRELVLRYA QEWALPEAFI QWLDQANSFC STLVDRIVTG YPRDEVAKLE 250 260 270 280 290 300 EELGYHDGFL DTAEHFYLFV IQGPKSLATE LRLDKYPLNV LIVDDIKPYK ERKVAILNGA 310 320 330 340 350 360 HTALVPVAFQ AGLDTVGEAM NDAEICAFVE KAIYEEIIPV LDLPRDELES FASAVTGRFR 370 380 390 400 410 420 NPYIKHQLLS IALNGMTKFR TRILPQLLAG QKANGTLPAR LTFALAALIA FYRGERNGET 430 440 450 460 470 480 YPVQDDAHWL ERYQQLWSQY RDRVIGTQEL VAIVLAEKDH WEQDLTQVPG LVEQVANDLD 490 AILEKGMREA VRPLC

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed: 19165319] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928162 Genomic DNA. Translation: CAR07850.2.
RefSeq	YP_002397627.1. NC_011745.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B7MUT4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000143632; EBESCP00000133405; EBESCG00000144668.
GeneID	7141001.
GenomeReviews	Gene locus ECED1_1653 in contig CU928162_GR.
PATRIC	38487307. VBIEscCol8292_1661.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000009063.
HOGENOM	HBG297101.
OMA	FIDWQID.
ProtClustDB	PRK03643.
Family and domain databases
HAMAP	MF_00670. Altron_oxidoreduct. [Tree]
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR023668. Altronate_OxRdtase. IPR013328. DH_multihelical. IPR013118. Mannitol_DH_C. IPR013131. Mannitol_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7MUT4_ECO81

Accession

Primary (citable) accession number: B7MUT4

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)